9 documents found, page 1 of 1
Influence of different local anesthetics on atracurium neuromuscular blockade o...
Trizotti,João Paulo Soares da Silva; Braga,Angélica de Fátima de Assunção; Carvalho,Vanessa Henriques; Braga,Franklin Sarmento da SilvaAbstract Introduction: The association between local anesthetics (LA) and neuromuscular blocking (NMB) drugs in clinical practice, and the possibility of interaction between these drugs has been investigated. LAs act on neuromuscular transmission in a dose-dependent manner and may potentiate the effects of NMB drugs. Objective: The aim of this study was to evaluate, in an experimental model, the effect of lidoc...
Combined spinal-epidural block for labor analgesia. Comparative study with cont...
Braga,Angélica de Fátima de Assunção; Carvalho,Vanessa Henriques; Braga,Franklin Sarmento da Silva; Pereira,Rosa Inês CostaAbstract Introduction: Lumbar epidural block is an effective and routinely used technique for labor pain relief, and the combined spinal-epidural block has the benefit of using lower doses of local anesthetics and rapid onset of analgesia. The objective of this study was to evaluate the effectiveness and safety of two anesthetic techniques: combined spinal-epidural block and continuous epidural block in pregnan...
Anesthesia for cesarean delivery in a patient with Klippel-Trenaunay syndrome
Teixeira,Clara Elisa Frare de Avelar; Braga,Angélica de Fátima de Assunção; Braga,Franklin Sarmento da Silva; Carvalho,Vanessa HenriquesAbstract Introduction: Klippel-Trenaunay syndrome is a rare congenital vascular disease characterized by cutaneous hemangiomas, varicosities, and limb asymmetry, which may evolve with coagulation disorders and hemorrhage as those more frequent complications in pregnant patients. Pregnancy is not advised in women with this syndrome due to increased obstetrical risk. Case report: Female patient, 29 years old, 99 ...
Use of protocol and evaluation of postoperative residual curarization incidence...
Santos,Filipe Nadir Caparica; Braga,Angelica de Fátima de Assunção; Ribeiro,Carla Josefine Barbosa de Lima; Braga,Franklin Sarmento da SilvaAbstract Objective Evaluate the incidence of postoperative residual curarization (PORC) in the post-anesthesia care unit (PACU) after the use of protocol and absence of intraoperative acceleromyography (AMG). Methods Randomized clinical trial with 122 patients allocated into two groups (protocol and control). Protocol group received initial and additional doses of rocuronium (0.6 mg·kg-1 and 10 mg, respectively...
Association between levobupivacaine and pancuronium. Interference in neuromuscu...
Carvalho,Vanessa Henriques; Braga,Angélica de Fátima de Assunção; Braga,Franklin Sarmento da Silva; Potério,Gloria Maria BragaABSTRACT PURPOSE: To evaluate the effects of levobupivacaine on neuromuscular transmission and neuromuscular blockade produced by pancuronium in vitro. METHODS: Thirty rats were distributed into groups (n = 5) according to the drug used alone or in combination: Group I - levobupivacaine (5 µg.mL-1); Group II - pancuronium (2 µg.mL-1); Group III - pancuronium (2 µg.mL-1) + levobupivacaine (5µg.mL-1). The followi...
Effect of ropivacaine combined with pancuronium on neuromuscular transmission a...
Braga,Angélica de Fátima; Carvalho,Vanessa Henriques; Braga,Franklin Sarmento; Potério,Gloria Maria Braga; Santos,Filipe Nadir CaparicaBACKGROUND AND OBJECTIVES: The local anesthetic effects on neuromuscular junction and its influence on blockade produced by nondepolarizing neuromuscular blockers are still under-investigated; however, this interaction has been described in experimental studies and in humans. The aim of this study was to evaluate in vitro the interaction between ropivacaine and pancuronium, the influence on transmission and neu...
Evidence of presynaptic and postsynaptic action of local anesthetics in rats
Braga,Angélica de Fátima de Assunção; Carvalho,Vanessa Henriques; Braga,Franklin Sarmento da Silva; Potério,Gloria Maria BragaPURPOSE: To assess the probable actions of ropivacaine, 50% enantiomeric excess bupivacaine mixture (S75-R25) and levobupivacaine on neuromuscular transmission in vitro. METHODS: Thirty rats were distributed into groups (n=5) according to the drug used: ropivacaine, bupivacaine (S75-R25) and levobupivacaine. The concentration used for the three local anesthetics (LA) was 5 µg.mL.-1The following parameters were ...
Influência de anestésicos locais sobre o bloqueio neuromuscular produzido pelo ...
Braga,Angélica de Fátima de Assunção; Carvalho,Vanessa Henriques; Braga,Franklin Sarmento da Silva; Rodrigues-Simioni,Léa; Loyola,Yolanda Christina SJUSTIFICATIVA E OBJETIVOS: Os efeitos dos anestésicos locais (AL) na transmissão neuromuscular e sua influência no bloqueio neuromuscular produzido por bloqueadores neuromusculares competitivos são ainda alvo de pouca investigação. O objetivo do estudo foi avaliar in vitro os efeitos da lidocaína e da mistura enantiomérica em excesso de 50% de bupivacaína (S75-R25) no bloqueio neuromuscular produzido pelo rocur...
The influence of lidocaine and racemic bupivacaine on neuromuscular blockade pr...
Carvalho,Vanessa Henriques; Braga,Angélica de Fátima de Assunção; Braga,Franklin Sarmento da Silva; Loyola,Yolanda Christina S.PURPOSE: To evaluate in vitro lidocaine and racemic bupivacaine effects in neuromuscular transmission and in neuromuscular blockade produced by rocuronium. METHODS: Rats were distributed in 5 groups (n = 5) in agreement with the studied drugs: lidocaine, racemic bupivacaine, rocuronium, separately (Groups I, II, III); rocuronium in preparations exposed to local anesthetics (Groups IV, V). The concentrations use...