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Generation of a triple-fluorescent mouse strain allows a dynamic and spatial vi...

Nakagaki, Brenda N.; Freitas-Lopes, Maria A.; Carvalho, Érika; Carvalho-Gontijo, Raquel; Castro-Oliveira, Hortência M.; Rezende, Rafael M.

Resident and circulating immune cells have been extensively studied due to their almost ubiquitous role in cell biology. Despite their classification under the “immune cell department”, it is becoming increasingly clear that these cells are involved in many different non-immune related phenomena, including fetus development, vascular formation, memory, social behavior and many other phenotypes. There is a huge ...

Date: 2018   |   Origin: Oasisbr

Infection of hematopoietic stem cells by Leishmania infantum increases erythrop...

Carvalho-Gontijo, Raquel; Moreira, Diana Raquel; Resende, Mariana; Costa-Silva, Matheus Fernandes; Peruhype-Magalhães, Vanessa

Immunosuppression is a well-established risk factor for Visceral Leishmaniasis. Post-immunosuppression leishmaniasis is characterized by an increase of parasite burden, hematopoietic disorders and unusual clinical manifestations. Although there are many reports on bone marrow findings in VL, less is known about the relationship between parasite dynamics in this organ and the function of either hematopoietic ste...


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