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The impact of war on asthma, a systematic review and meta-analysis: An EAACI ta...

Rufo, João Cavaleiro; Paciência, Inês; Jutel, Marek; Moreira, André; Annesi-Maesano, Isabella; Suojalehto, Hille; Zemelka-Wiącek, Magdalena

Wartime events have been followed by an increase in asthma prevalence, which is believed to result from a combination of environmental hazards and psychological trauma. This systematic review and meta-analysis aimed to investigate this relationship by pooling available data on various wartime exposures, such as occupational, environmental, and psychological factors. MEDLINE, Scopus, and Cochrane databases were ...


Editorial comments on “Multiarray screening identifies plasma proteins associat...

Rufo, João Cavaleiro; Chauhan, Jitesh; Kalayci, Ömer; Eigenmann, Philippe; Cavaleiro Rufo, João

The clinical associations between asthma and obesity remain poorly understood. The increasing prevalence ofboth conditions occurring may represent a modern clinical paradox. It is unclear whether reduced physical activ-ity in children with asthma leads to obesity, or if asthma-like symptoms in obese children result directly from theassociated excessive abdominal fat, impaired lung function, and heightened Th2 i...


The Influence of Obesity in the Autonomic Nervous System Activity in School-Age...

Gonçalves Teixeira, Beatriz; Paciência, Inês; Cavaleiro Rufo, João; Mendes, Francisca; Farraia, Mariana; Padrão, Patrícia; Moreira, Pedro

Introduction: Obesity is one of the most prevalent chronic diseases in childhood, being an important public health issue. Excessive weight has been associated with autonomic dysfunction but the evidence in children is scarce. Therefore, the aim of this study was to assess the effect of overweight and obesity on the autonomic nervous system activity, in children.Material and Methods: Data from a cross-sectional ...

Data: 2023   |   Origem: Acta Médica Portuguesa

Diet quality and airway inflammation in school aged children

Rodrigues, Mónica; de Castro Mendes, Francisca; Paciência, Inês; Cavaleiro Rufo, João; Silva, Diana; Delgado, Luís; Moreira, André; Moreira, Pedro


Detection and identification of fungal species by electronic nose technology: A...

Mota, Inês; Teixeira-Santos, Rita; Cavaleiro Rufo, João

A rapid and effective identification of fungal species is essential for numerous applications, and electronic nose systems are being proposed as suitable alternatives to currently available fungi identification techniques. Hence, the present review aims to unveil all published information concerning fungi identification by electronic nose systems. A systematic review of the literature was conducted according to...


Indoor fungal diversity in primary schools may differently influence allergic s...

Cavaleiro Rufo, João; Madureira, Joana; Paciência, Inês; Aguiar, Lívia; Pereira, Cristiana; Silva, Diana; Padrão, Patrícia; Moreira, Pedro

Childhood exposure to microbiologic agents may influence the development of allergic and respiratory diseases. Apart from home, children spend most of their time at school, which represents an environment of significant exposure to indoor air microbes. Therefore, we aimed to assess how the prevalence of allergic sensitization and asthma in schoolchildren is affected by microbiologic exposure within classrooms.


Bacterial and fungal exposure in schools may influence asthma and allergy in ch...

Cavaleiro Rufo, João; Madureira, J.; Paciência, I.; Aguiar, L.; Delgado, L.; Teixeira, J.P.; de Oliveira Fernandes, E.; Moreira, A.

Development of allergic diseases may be regulated by microbial exposure. Children spend a lot of their time in schools, under an extensive diversity of biological agents, such as bacteria and fungi. This study aimed to characterize indoor air microbiological exposure in schools as a predictor of allergic sensitization and asthma in children.


The Impact of Indoor Exposure to Fungi and Bacteria on the Risk of Sensitizatio...

Cavaleiro Rufo, João; Madureira, Joana; Paciência, Inês; Aguiar, Lívia; Padrão, Patrícia; Pinto, Mariana; Delgado, Luísa; Moreira, Pedro

Aim: To characterize indoor air microbiological exposure in schools as a predictor of allergic sensitization and asthma in children.


Children exposure to indoor ultrafine particles in urban and rural school envir...

Cavaleiro Rufo, João; Madureira, Joana; Paciência, Inês; Slezakova, Klara; Pereira, Maria do Carmo; Aguiar, Lívia; Teixeira, João Paulo; Moreira, André

Extended exposure to ultrafine particles (UFPs) may lead to consequences in children due to their increased susceptibility when compared to older individuals. Since children spend in average 8 h/day in primary schools, assessing the number concentrations of UFPs in these institutions is important in order to evaluate the health risk for children in primary schools caused by indoor air pollution. Thus, the purpo...


Indoor air quality and atopic sensitization in primary schools: A follow-up study

Cavaleiro Rufo, João; Madureira, Joana; Paciência, Inês; Aguiar, Lívia; Teixeira, João Paulo; Moreira, André; de Oliveira Fernandes, Eduardo

Background: The onset and exacerbation of allergic diseases and asthma have been associated with poorindoor air quality (IAQ) inside classrooms.Objective: The aim was to investigate how IAQ changed in primary schools after applying indoor air qualityrecommendations, and to explore how these changes influenced allergic sensitization on children.Methods: Total volatile organic compounds, PM2.5, PM10, CO2, CO, tem...


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