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Interferon-gamma release assay performance in northeastern Brazil: influence of...

Carneiro,Valdirene Leão; Bendicho,Maria Teresita; Santos,Rosalina Guedes; Casela,Marilda; Netto,Eduardo M.; Mota,Scarlet Torres Moraes

ABSTRACT Introduction Latent tuberculosis infection diagnosis based on the release of interferon-gamma in cultures of peripheral blood cells stimulated with Mycobacterium tuberculosis antigens has replaced the tuberculin skin test in many countries with low tuberculosis prevalence. The IFN-γ production can be influenced by genetic polymorphisms, of which the IFNG + 874 (rs62559044) locus is the most studied. We...

Date: 2018   |   Origin: Oasisbr

Rapid molecular test for tuberculosis: impact of its routine use at a referral ...

Casela,Marilda; Cerqueira,Silvânia Maria Andrade; Casela,Thais de Oliveira; Pereira,Mariana Araújo; Santos,Samanta Queiroz dos; Pozo,Franco Andres Del

ABSTRACT Objective: To evaluate the impact of the use of the molecular test for Mycobacterium tuberculosis and its resistance to rifampin (Xpert MTB/RIF), under routine conditions, at a referral hospital in the Brazilian state of Bahia. Methods: This was a descriptive study using the database of the Mycobacteriology Laboratory of the Octávio Mangabeira Specialized Hospital, in the city of Salvador, and georefer...

Date: 2018   |   Origin: Oasisbr

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