12 documents found, page 1 of 2
Fighting HIV/AIDS in a developing country: lessons from a small cohort from the...
Casseb, Jorge; Veiga, Ana Paula R.; Magri, Marcello M. C.; Monteiro, Mariana A.; Rocha, Rosana C.; Gascon, Maria Rita P.; Domingues-Ferreira, MauricioNot Applicable
Is the telomere length associated with neurocognitive disabilities in HIV-1-inf...
Araújo, Marilia Ladeira de; Duarte, Wellington; Oliveira, Augusto César Penalva de; Gascón, Maria Rita Polo; Fonseca, Luiz Augusto MarcondesObjective: We evaluated the association between cognitive deficits and leukocyte telomere length (LTL) in HIV-1-infected individuals. Design: 73 HIV-1-infected patients undergoing neuropsychological evaluation and 91 healthy controls were included in this study. Fifteen HIV-1 positive patients did not have cognitive disorders whereas 26 had asymptomatic neurocognitive disorder (ANI), 13 presented mild to modera...
Low bone mineral density among HIV-infected patients in Brazil
Chaba, Daniela Cardeal da Silva; Soares, Lisméia R.; Pereira, Rosa M. R.; Rutherford, George W.; Assone, Tatiane; Takayama, Liliam; Fonseca, Luiz A. M.Decrease in bone mineral density (BMD) has been a complication among people living with HIV/AIDS. To investigate the prevalence of osteopenia/osteoporosis among HIV-infected people living in São Paulo city, we studied 108 HIV-infected patients (79 men and 29 women). We extracted data from patients’ medical records and BMD was measured by dual-energy X-ray absorptiometry (DXA). Median age of participants was 42 ...
Depression and adherence to antiretroviral treatment in HIV-positive men in São...
Moraes, Ricardo Pereira de; Casseb, JorgeOBJECTIVES: The aim of the present study was to investigate the prevalence of depression and adherence to antiretroviral treatment in two groups of individuals: men who have sex with men (MSM) and men who have sex with women (MSW). METHODS: Two hundred and sixteen participants (MSM=116; MSW=100) who visited the Clinics Hospital of the School of the Medicine of the University of São Paulo completed two independe...
Origem e prevalência do vírus linfotrópico de células T humanas em populações i...
Paiva, Arthur; Casseb, JorgeHuman T-lymphotropic virus type 1 (HTLV-1) is found in indigenous peoples of the Pacific Islands and the Americas, whereas type 2 (HTLV-2) is widely distributed among the indigenous peoples of the Americas, where it appears to be more prevalent than HTLV-1, and in some tribes of Central Africa. HTLV-2 is considered ancestral in the Americas and is transmitted to the general population and injection drug users f...
DETERMINATION OF VIRAL TROPISM BY GENOTYPING AND PHENOTYPING ASSAYS IN BRAZILIA...
Arruda, Liã Bárbara; Araújo, Marilia Ladeira de; Martinez, Maira Luccia; Gonsalez, Claudio Roberto; Duarte, Alberto José da Silva; Coakley, EoinThe clinical application of CCR5 antagonists involves first determining the coreceptor usage by the infecting viral strain. Bioinformatics programs that predict coreceptor usage could provide an alternative method to screen candidates for treatment with CCR5 antagonists, particularly in countries with limited financial resources. Thus, the present study aims to identify the best approach using bioinformatics to...
Association between muscle strength and the cardiopulmonary status of individua...
Raso, Vagner; Shephard, Roy J.; Casseb, Jorge; Duarte, Alberto José da Silva; Silva, Paulo Roberto Santos; Greve, Júlia Maria D'AndréaOBJECTIVE: The purpose of this study was to compare aerobic function [anaerobic threshold (%VO2-AT), respiratory compensation point (%VO2-RCP) and peak oxygen uptake (VO2peak)] between physically active patients with HIV/AIDS and matched controls and to examine associations between disease status, poor muscle strength, depression (as estimated by the profile of mood states questionnaire) and the aerobic perform...
Tuberculose entre pacientes infectados pelo HIV-1 em ambulatório terciário de S...
Casseb, Jorge; Fonseca, Luiz Augusto M.; Medeiros, Lucas A.; Gonsalez, Claudio R.; Lagonegro, Eduardo R.; Veiga, Ana Paula Rocha; Silva, Daniela C. daAtualmente, a tuberculose (TB) é considerada a doença infecciosa mais importante entre os pacientes infectados pelo HIV-1 nos países em desenvolvimento, como o Brasil. Análise retrospectiva dos casos de tuberculose ocorridos a partir de janeiro 1995 até dezembro de 2010 foi realizada em nossa coorte de 599 pacientes HIV positivos. O desfecho primário foi a ocorrência de TB ativa, e 41 casos da doença foram diag...
Influência da infecção pelo vírus linfotrópico humano tipo 1 (HTLV-1) em parâme...
Cardoso, Daniela Fernandes; Souza, Fernando Vieira de; Fonseca, Luiz Augusto M.; Duarte, Alberto José da Silva; Casseb, JorgeHepatitis C virus (HCV) and human T-cell lymphotropic virus type 1 (HTLV-1) share routes of transmission and some individuals have dual infection. Although some studies point to a worse prognosis of hepatitis C virus in patients co-infected with HTLV-1, the interaction between these two infections is poorly understood. This study evaluated the influence of HTLV-1 infection on laboratory parameters in chronic HC...
Distribution of hepatitis B virus genotypes and viral load levels in Brazilian ...
Alcalde, Rosana; Melo, Fernando Lucas; Nishiya, Anna; Ferreira, Suzete Cleusa; Langhi Júnior, Mario Dante; Fernandes, Simone SenaO objetivo do presente estudo foi avaliar a carga viral no soro de pacientes cronicamente infectados pelo vírus da Hepatite B (HBV) e investigar a distribuição de genótipos HBV na cidade de São Paulo. PCR quantitativo do HBV e genotipagem ganharam importância para a previsão de progressão da doença, empregada para avaliar a infectividade, para tratamento e acompanhamento e para detectar o aparecimento de resist...