3 documents found, page 1 of 1
TERTp mutations and p53 expression in head and neck cutaneous basal cell carcin...
Castanheira, A; Vieira, MJ; Pinto, M; Dias, C; Prada, L; Macedo, S; Fernandes, MS; Vieira, F; Soares, P; Mota, AV; Lopes, JM; Boaventura, PCutaneous basal cell carcinoma (cBCC) is an economic burden to health services, due to its great morbidity and increasing incidence in old people. Infiltrative cBCCs and cBCCs with micronodular pattern are considered as more aggressive. The role of p53 expression and TERTp mutation on cBCC behavior remains to be clarified. We aimed to assess TERTp mutations and p53 expression in relation to the cBCC histologica...
Head and neck cutaneous basal cell carcinoma: What should the otorhinolaryngolo...
Castanheira, A; Boaventura, P; Clemente, MP; Soares, P; Mota, AV; Lopes, JMCutaneous basal cell carcinoma (cBCC) is the most common malignancy diagnosed in the human population. cBCC presents an increasing incidence which, in the near future, will be higher than all other cancers combined. The majority of cBCC are located in the head and the neck. A diversity of management modalities is currently available; nonetheless, surgical excision remains the main modality of treatment. cBCC ra...
Oesophageal lichen planus
Souto, P; Sofia, C; Pina-Cabral, JE; Castanheira, A; Saraiva, S; Tellechea, O; Donato, A; Freitas, DLichen planus is a common skin and mucosal disease, with very rare symptomatic oesophageal involvement. We report a case of painful dysphagia due to oesophageal lichen planus in a 60-year-old woman who also had oral, cutaneous and genital lichen planus lesions. Steroid treatment produced considerable improvement of all lesions and a rapid symptomatic remission.