Encontrados 105 documentos, a visualizar página 1 de 11
Shedding light on toxicity of SARS-CoV-2 peptides in aquatic biota: A study inv...
Mendonça-Gomes, Juliana Moreira; Charlie-Silva, Ives; Guimarães, Abraão Tiago Batista; Estrela, Fernanda Neves; Calmon, Marilia Freitas [UNESP]Made available in DSpace on 2022-04-29T08:45:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-15; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Instituto Federal Goiás; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Knowledge about how the COVID-19 pandemic can affect aquatic wildlife is still extremely limited, and no effect of SARS-CoV-2 or its structural co...
Detection of Zika virus in urine from randomly tested individuals in Mirassol, ...
da Conceição, Pâmela Jóyce Previdelli [UNESP]; de Carvalho, Lucas Rodrigues [UNESP]; de Godoy, Bianca Lara Venâncio; Nogueira, Mauricio LacerdaMade available in DSpace on 2022-04-29T08:45:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Purpose: Studies show that around 80% of Zika virus (ZIKV) infections are asymptomatic. The present st...
Detection of hepatitis C virus resistant mutants in the era of direct acting an...
Rossi, Livia Maria Gonçalves [UNESP]; Rahal, Paula [UNESP]Made available in DSpace on 2022-04-29T12:27:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-01-01; Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, the arrival of a plethora of novel, more powerful drugs has revolutionized the fiel...
Detection of hepatitis C virus resistant mutants in the era of direct acting an...
Rossi, Livia Maria Gonçalves [UNESP]; Rahal, Paula [UNESP]Made available in DSpace on 2022-04-29T15:03:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-01-07; Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, the arrival of a plethora of novel, more powerful drugs has revolutionized the fiel...
The Emergence of the New P.4 Lineage of SARS-CoV-2 With Spike L452R Mutation in...
Bittar, Cíntia [UNESP]; Possebon, Fábio Sossai [UNESP]; Ullmann, Leila Sabrina [UNESP]; Geraldini, Dayla Bott [UNESP]; da Costa, Vivaldo G. [UNESP]Made available in DSpace on 2022-04-29T08:35:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-01; Financiadora de Estudos e Projetos; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Center for Information Technology; Center for Scientific Review; National Institutes of Health; Office of Extramural Research, National...
Effects of photodynamic therapy mediated by emodin in cervical carcinoma cells
Galiardi-Campoy, Ana Emília Brumatti [UNESP]; Machado, Francielly Cristina [UNESP]; Carvalho, Tamara [UNESP]; Tedesco, Antonio ClaudioMade available in DSpace on 2022-04-29T08:29:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-01; Cervical cancer is a worldwide public health problem, and improved selective therapies and anticancer drugs are urgently needed. In recent years, emodin has attracted considerable attention due to its anti-inflammatory, antineoplastic, and proapoptotic effects. Furthermore, emodin may be used as a photo...
Case study of two post vaccination SARS-CoV-2 infections with P1 variants in co...
Estofolete, Cassia F.; Banho, Cecilia A.; Campos, Guilherme R.F.; Marques, Beatriz C.; Sacchetto, Livia; Ullmann, Leila S. [UNESP]Made available in DSpace on 2022-05-01T06:02:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-01; The rapid development of efficacious and safe vaccines against coronavirus disease 2019 (COVID-19) has been instrumental in mitigating the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Moreover, the emergence of SARS-CoV-2 variants raised concerns on the efficacy of these...
Curcumin-cinnamaldehyde hybrids as antiproliferative agents against women’s can...
Anselmo, Daiane B. [UNESP]; Polaquini, Carlos R. [UNESP]; Marques, Beatriz C. [UNESP]; Ayusso, Gabriela M. [UNESP]; Assis, Letícia R. [UNESP]Made available in DSpace on 2022-05-01T08:44:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Curcumin and cinnamaldehyde are natural products whose antineoplastic activity has been well explored in biological evaluations. However, their poor chemical stability under physiological conditions has been an obstacle to their use as therapeutic agents. Herein, we designed and synthesized two series o...
Recent advances in SARS-CoV-2 Spike protein and RBD mutations comparison betwee...
Sanches, Paulo R.S. [UNESP]; Charlie-Silva, Ives; Braz, Helyson L.B.; Bittar, Cíntia [UNESP]; Freitas Calmon, Marilia [UNESP]; Rahal, Paula [UNESP]Made available in DSpace on 2022-05-01T09:30:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); New variants of SARS-CoV-2 Alpha (B.1.1.7); Beta (B.1.351) Gamma (P.1) and Delta (B.1.617.2) quickly spread in the UK, South Africa, Brazil and India, respectively. To address whether mutations in SARS-CoV-2 RBD spike protein could affect vi...
Gene mutations and polymorphisms of TP53 and FHIT in chronic esophagitis and es...
Silveira, Aparecida Perpetuo Fedossi [UNESP]; Manoel-Caetano, Fernanda Da Silva [UNESP]; Aoki, Sérgio [UNESP]; Yamasaki, Lílian Hiromi Tomonari [UNESP]Made available in DSpace on 2022-04-28T22:37:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-05-01; Aim: The aim of this study was to investigate genetic changes of the TP53 (tumor protein p53) and FHIT (fragile histidine triad) genes in precursor lesion such as chronic esophagitis (CE) and in esophageal squamous cell carcinoma (ESCC). Materials and Methods: PCR-Single Strand Conformation Polymorphism...