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Dual Retinitis with Cytomegalovirus and Herpes Simplex in a Paediatric Patient ...

Herpesvirus retinitis is a serious infection of the retina typically found in immunosuppressed patients. We report the case of a 4-year-old boy with a history of enucleation of the left eye for intraocular advanced retinoblastoma, at time under systemic adjuvant chemotherapy, observed under anaesthesia for periodic disease follow-up. Right eye fundus evaluation showed multiple areas of focal haemorrhagic retini...

Tocilizumab no Tratamento da Orbitopatia de Graves

Introdução: A orbitopatia de Graves (GO) é uma doença inflamatória autoimune com tratamento desafiante e algo controverso. As opções terapêuticas na doença ativa moderada a grave podem incluir a terapêutica endovenosa com corticoides, outros imunomoduladores, radioterapia ou descompressão cirúrgica da órbita. O Clinical Activity Score (CAS) é uma escala clínica que quantifica os sinais e sintomas...

The Cost of Meningococcal Meningitis in Portugal

Introduction: Invasive meningococcal disease (IMD) is an infection caused by the bacterium Neisseria meningitidis, and a major cause of meningitis (MM) and/or septicemia (MS). The aim of this study is to estimate the costs of IMD (MM and MS) for Portuguese state.Methods: To estimate the costs associated with IMD, a model was developed, where patients can have one of three outcomes: survive without sequelae, sur...

Effectiveness of Intra-Arterial Chemotherapy for the Treatment of Intraocular R...

Purpose: We aim to report about effectiveness and safety in the context of our centers’ setting in the management of retinoblastoma with intra-arterial chemotherapy (IAC) in a 5-year retrospective analysis of the Portuguese population. Patients and Methods: Retrospective analysis of consecutive cases of retinoblastoma selected to initiate IAC between 2015 and 2020, at the Portuguese National Reference Center. A...

Optical Coherence Tomography (OCT) in Retinoblastoma Management: Experience of ...

INTRODUCTION: Patients under 5 years old with retinoblastoma require close monitoring under anesthesia to ensure early detection of new tumors. They undergo monthly observations after diagnosis and during the first 6 months after treatment, then observations are gradually spaced in time until the age of five. Optical coherence tomography (OCT) is a relatively new exam in monitoring retinoblastoma patients. The ...

Arbitragem no turismo : uma oportunidade de lucro?

Characterization of the Portuguese population diagnosed with retinoblastoma

The purpose of this study is to characterize demographically and genetically the Portuguese population with retinoblastoma; to report the clinical stage at presentation and its impact on survival and ocular preservation rate and, finally, to assess the incidence of retinoblastoma in Portugal. Retrospective observational study including children consecutively diagnosed with retinoblastoma at the Portuguese Natio...

Housing in Portugal (1992-2008) a multidimensional perspective on the behaviour...

Since the nation joined the European Union, the process that regulates housing policy in Portugal has been subject to specificities that are proper of the Portuguese situation. In a State which has a considerable housing deficit, it was the quantifier elements that judged the various governments regarding this matter. Almost all of the housing production depended on mortgage loans in which soft loans played an ...

Treatment of Advanced Retinoblastoma in Children Evacuated from Low-Income Coun...

Objective: The aim of our study was to characterize the evacuated African patients diagnosed with retinoblastoma and referred to the Portuguese national referral center (Centro Hospital e Universitário de Coimbra, University of Coimbra), identifying inequalities in the stage of diagnosis and prognostic results. Design: Retrospective observational study of evacuated African patients diagnosed with retinoblastoma...

Three-Way Multiblock Methods for Decision-Making in Health Services: A COSTATIS...

In the last decade, the clinical laboratory sector in Portugal has witnessed an increase in competition through the integration of small private laboratories in multinational organizations. In this competition scenario, it is imperative that decisions related to management are made based on the analysis of varied and detailed information data in order to propose strategies and prioritize management. Thus, the g...