234 documents found, page 1 of 24
Therapeutic benefits of a 16-week compassion focused therapy for overeating are...
Marques, Cristiana C.; Sayal, Alexandre; Goss, Kenneth; Correia, Rita; Castilho, Paula; Pereira, Ana T.; Castelo-Branco, Miguel; Palmeira, LaraObjective: Compassion Focused Therapy (CFT) has shown promise in reducing shame and self- criticism and enhancing compassion in individuals with eating difficulties. However, the neurophysiological mechanisms, particularly those related to learning, are not well understood. This longitudinal study investigated the neurophysiological effects of an online CFT for overeating (CFT- OE) using functional magnetic res...
Epidemiological profile and antibiotic resistance in urinary tract infections a...
Rodrigues, Francisco; Patricia Coelho; Mateus, Sónia; Metello, João; Castelo-Branco, MiguelUrinary tract infections (UTIs) are among the most prevalent infectious diseases in older women, especially those over 65 years of age. Physiological changes related to aging, comorbidities, and frequent use of medical devices such as urinary catheters increase susceptibility. Increasing antimicrobial resistance further complicates treatment strategies. This study aims to describe the epidemiological profile of...
Burnout protective patterns among oncology nurses: a cross-sectional study usin...
Rocha, Ana; Costeira, Cristina; Barbosa, Raul; Gonçalves, Florbela; Castelo-Branco, Miguel; Viana, Joaquim; Gaudêncio, Margarida; Ventura, FilipaBackground Oncology nurses face unique and intense demands due to the nature of their work, caring for patients with life-threatening illnesses. The emergence of professional burnout among these nurses is influenced by several factors, highlighting the importance of identifying protective and risk factors to mitigate its impact. This study aims to identify burnout profiles and protective socio-demographic and w...
Intestinal mucosal alterations parallel central demyelination and remyelination...
Ferreira, Carolina; Carvalho, Filipa; Vieira, Pedro; Alves, André; Palavra, Filipe; Almeida, Jani; Alves, Vera; Coscueta, EzequielBackground: The gut-brain axis has been increasingly recognized as a critical factor in Multiple Sclerosis (MS) pathophysiology. While its role in demyelination is well documented, gut-brain axis involvement during remyelination remains largely unexplored. Methods: Using the cuprizone (CPZ) model, which induces reversible demyelination and spontaneous remyelination upon toxin withdrawal, we investigated gut and...
Neurometabolic profiles of autism spectrum disorder patients with genetic varia...
Vilela, Joana; Pereira, Andreia C.; Violante, Inês R.; Mouga, Susana; Rasga, Célia; Santos, João Xavier; Martiniano, Hugo; Marques, Ana RitaAutism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by impaired social interaction, and restricted and repetitive patterns of behavior. ASD presents as a clinical spectrum, with variable levels of severity and multiple co-occurring conditions. The etiology of ASD may involve hundreds of genes and there is evidence that neurotransmitter and synaptic (NS) pathways are implicated. Proton...
Burnout protective patterns among oncology nurses: a cross-sectional study usin...
Rocha, Ana; Costeira, Cristina; Barbosa, Raul; Gonçalves, Florbela; Castelo-Branco, Miguel; Viana, Joaquim; Gaudêncio, Margarida; Ventura, FilipaBackground: Oncology nurses face unique and intense demands due to the nature of their work, caring for patients with life-threatening illnesses. The emergence of professional burnout among these nurses is influenced by several factors, highlighting the importance of identifying protective and risk factors to mitigate its impact. This study aims to identify burnout profiles and protective socio-demographic and ...
Cognitive Stimulation and Dementia: Traditional Interventions vs. Computer-Base...
Mendes, Liliana; Castelo-Branco, Miguel; Oliveira, JoanaWe aim to examine the role of cognitive stimulation interventions applied to healthy older adults or older adults with mild-to-moderate dementia. The most important benefits and differences between using these programs without computerised tasks compared to computer-based assistive technologies are also addressed. We conducted a literature review which includes empirical studies in the cognitive stimulation fie...
Polyphenols: immunonutrients tipping the balance of immunometabolism in chronic...
Ferreira, Carolina; Vieira, Pedro; Sá, Helena Manuel Pina de Oliveira e; Malva, João Oliveira; Castelo-Branco, MiguelMounting evidence progressively appreciates the vital interplay between immunity and metabolism in a wide array of immunometabolic chronic disorders, both autoimmune and non-autoimmune mediated. The immune system regulates the functioning of cellular metabolism within organs like the brain, pancreas and/or adipose tissue by sensing and adapting to fluctuations in the microenvironment's nutrients, thereby reshap...
A Deep Learning-Based Integrated Framework for Quality-Aware Undersampled Cine ...
Machado, Inês; Puyol-Anton, Esther; Hammernik, Kerstin; Cruz, Gastao; Ugurlu, Devran; Olakorede, Ihsane; Oksuz, Ilkay; Ruijsink, BramCine cardiac magnetic resonance (CMR) imaging is considered the gold standard for cardiac function evaluation. However, cine CMR acquisition is inherently slow and in recent decades considerable effort has been put into accelerating scan times without compromising image quality or the accuracy of derived results. In this article, we present a fully-automated, quality-controlled integrated framework for reconstr...
Distinct oscillatory patterns differentiate between segregation and integration...
Costa, Gabriel Nascimento; Schaum, Michael; Duarte, João Valente; Martins, Ricardo; Duarte, Isabel Catarina; Castelhano, João; Wibral, MichaelRecently, there has been a resurgence in experimental and conceptual efforts to understand how brain rhythms can serve to organize visual information. Oscillations can provide temporal structure for neuronal processing and form a basis for integrating information across brain areas. Here, we use a bistable paradigm and a data-driven approach to test the hypothesis that oscillatory modulations associate with the...