11 documents found, page 1 of 2
Why do we Discontinue Biologic Agents? A Retrospective Study of 11 Years
Gil, Francisco; Rato, Margarida; Monteiro, Ana; Parente, Joana; Martins, César; Aranha, João; Silva, Maria JoãoIntroduction: Biologic agents acquired a growing relevance in dermatology, however, adverse events (AE) and reasons to discontinue therapy are not completely known. The objective of this study is to analyse the reasons behind the discontinuation of biologics and characterize the AE in this population of patients. Material and Methods: Descriptive observational study, including patients over 18-years-old under t...
Sclerotherapy in the Treatment of Familial Disseminated Cutaneous Glomuvenous M...
Gil, Francisco; Ortiz, Santiago; Aranha, JoãoGlomuvenous malformations usually present as soft bluish-purple dermal or subcutaneous papules, nodules or plaques, and can occur as sporadic or inherited lesions. We present the case of a 41-year-old female, referred for evaluation of disseminated bluish lesions developing since puberty. Histopathology was consistent with the diagnosis of glomuvenous malformations. The history of a sister with similar lesions ...
Dermatology clinical case
Gil, Francisco; Aranha, João; Silva, Maria João; Andrade, IsabelHere in is reported the case of a child observed due to disseminated papulosquamous eruption, subsequently diagnosed as pityriasis lichenoides et varioliformis acuta. It is an uncommon dermatosis of unclear etiology, presenting as recurrent crops of scattered erythematous and violaceous maculopapules. Several therapeutic options have been proposed. Although clinical course is typically benign, continued monitor...
ORF DISEASE
Toda Brito, Helena; Tavares, Ermelindo; Aranha, João.; .
BIOLOGIC THERAPY IN ATOPIC ECZEMA
Sanches de Brito, Helena; Tavares, Ermelindo; Parente, Joana; Aranha, João; Silva, Maria JoãoAtopic eczema is a common inflammatory skin disease, affecting up to 20% of children and 3% of adults in industrialized countries. Most cases of atopic eczema are mild to moderate and will be adequately managed with topical therapy. Persistent or severe cases may require periods of systemic treatment, which can be broadly grouped into conventional and biologic agents. Conventional systemic agents are associated...
First autochthone case of sporotrichosis by Sporothrix globosa in Portugal
Oliveira, Manoel Marques Evangelista de; Verissimo, Cristina; Sabino, Raquel; Aranha, João; Zancope-Oliveira, Rosely Maria; Sampaio, Paula; Pais, CéliaIn this study, we characterize the first autochthone case of human sporotrichosis reported in Lisbon, Portugal. Phenotypic and genotypic characterization revealed that the infection was caused by Sporothrbc globosa. We conclude that sporotrichosis may be underdiagnosed particularly in Southern Europe and suggest Portugal as an emerging area for this fungal infection.
PYODERMA GANGRENOSUM ASSOCIATED WITH CHRONIC HEPATITIS C SUCCESSFULLY TREATED W...
Tavares, Ermelindo; Dores, José Alberto; Aranha, JoãoIntroduction: Pyoderma gangrenosum (PG) is an idiopathic, recurrent, neutrophilic and ulcerative skin disease. Case report: A 43-year-old man with chronic hepatitis C and drugs addiction in the past presented with a 6-months history of painful, violaceus, suppurative and necrotic ulcers on his lower extremities and any skin area inju- red by needle stick. PG was the main diagnosis proposed. Histological examina...
VULVAR LICHEN SCLEROSUS – A REVIEW OF 208 CASES
Torres, Ermelindo; Parente, Joana; Almeida, J. C.; Teixeira, José; Martins, César; Aranha, JoãoIntroduction: Lichen sclerosus (LS) is a chronic idiopathic inflammatory disease that preferentially affects the anogenital region and postmenopausal Caucasian women. Aims: Retrospective characterization of patients with vulvar LS diagnosed and treated at our Department (Vulvar Pathology Consultation), between 1986 and 2004. Material and Methods: A total of 208 Caucasians women were included in the study. We co...
CRYOSURGERY IN THE TREATMENT OF NON-MELANOMA SKIN CANCER OF THE EYELID AND PERI...
Tavares, Ermelindo; Gonçalves, J. C. Almeida; Aranha, JoãoIntroduction: Cryosurgery is a safe and effective treatment modality for non-melanoma skin cancers of the eyelids and periocular area, with a reported 5-year overall cure rate above 95%. Aim: Retrospective characterization of patients with non-melanoma skin cancer of eyelids and periocular regions diagnosed and treated with cryosurgery at our Department, between 1988 and 2004. Material and Methods: Review of th...
SCROTAL GIANT POLYPOID BASAL CELL CARCINOMA
Parente, Joana; Tavares, Ermelindo; Dores, José Alberto; Aranha, João; Marques, Maria de São José; Gomes, HelenaBasal cell carcinomas arising on the genitalia and over 5 cm in size are exceedingly rare. We report a case of a 60-year-old man with a lesion on the scrotum which had been slowly enlarging over the previous year. On examination he had an erythematous plaque 6.0x5.0cm in size with a pedunculated nodule. We performed an incisional biopsy. The histopathological diagnosis was basal cell carcinoma. The tumor was su...