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Differences in the response to TNF inhibitors at distinct joint locations in pa...

Ciurea, Adrian; Kissling, Seraphina; Götschi, Andrea; Ørnbjerg, Lykke Midtbøll; Rasmussen, Simon Horskjær; Tamási, Bálint; Möller, Burkhard

Publisher Copyright: © The Author(s) 2025.; Background: Efficacy of tumour necrosis factor inhibitors (TNFi) for peripheral arthritis in patients with psoriatic arthritis (PsA) has been established in randomized clinical trials that have used improvement in summated joint counts as an outcome. Whether joints at different anatomical locations might respond differentially to TNFi remains unknown. The aim of the s...


Second and third TNF inhibitors in European patients with axial spondyloarthritis

Linde, Louise; Ørnbjerg, Lykke Midtbøll; Brahe, Cecilie Heegaard; Wallman, Johan Karlsson; Di Giuseppe, Daniela; Závada, Jakub; Castrejon, Isabel

OBJECTIVE: To investigate real-world effectiveness of tumor necrosis factor inhibitors (TNFi) in patients with axial spondyloarthritis (axSpA) and the association with 1) treatment line (second and third TNFi-series) and 2) reason for withdrawal from the preceding TNFi (lack of efficacy (LOE) versus adverse events (AE)). METHODS: Prospectively collected routine care data from 12 European registries were pooled....


Recording of non-musculoskeletal manifestations, comorbidities and safety outco...

Ahmadzay, Zohra F.; Heberg, Jette; Jørgensen, Jacob B.; Ørnbjerg, Lykke M.; Østergaard, Mikkel; Møller-Bisgaard, Signe; Michelsen, Brigitte

Funding Information: This work was supported by Novartis Pharma AG. EuroSpA was financially supported by Novartis. Novartis had no influence on the data collection, statistical analyses, manuscript preparation or decision to submit the manuscript. Publisher Copyright: © 2024 The Author(s).; Objectives: Real-world evidence is needed to inform treatment strategies for patients with PsA and axial SpA (axSpA) who h...


Effectiveness of secukinumab in radiographic and non-radiographic axial spondyl...

Christiansen, Sara Nysom; Rasmussen, Simon Horskjær; Ostergaard, Mikkel; Pons, Marion; Michelsen, Brigitte; Pavelka, Karel; Codreanu, Catalin

Funding Information: Novartis Pharma AG for supporting the EuroSpA collaboration. The paper has been presented at the Scandinavia Congress of Rheumatology 2023 as an oral presentation and at the EULAR 2023 Congress as a poster presentation (POS0656) with the following abstract: SNC, SHR, LMO, etc. Does radiographic status impact secukinumab effectiveness in European axial spondyloarthritis patients treated in r...


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