The host immunologic response to a specific material is a critical aspect when considering it for clinical implementation. Collagen and gelatin extracted from marine sources have been proposed as biomaterials for tissue engineering applications, but there is a lack of information in the literature about their immunogenicity. In this work, we evaluated the immune response to collagen and/or gelatin from blue sha...
Gellan gum is an extracellular microbial polysaccharide from Sphingomonas paucimobilis that forms a firm and transparent gel in the presence of metallic ions. This hydrogel presents some interesting features that allow its use as a cell encapsulating support, or as an in vivo injectable system. In this work, the usefulness of gellan gum hydrogels as supports for cartilage tissue engineering applications was sho...
Gellan gum is an extracellular microbial polysaccharide from Sphingomonas paucimobilis that forms a firm and transparent gel in the presence of metallic ions. This hydrogel presents some in- teresting features that allow its use as a cell encapsulating support, or as an in vivo injectable system. In this work, the usefulness of gellan gum hydrogels as supports for cartilage tissue engineering applications was s...
[Excerpt] Chitosan-based biomaterials proved to have promising characteristics for wound dressing and skin regeneration. In the context of developing new natural-based biomaterials for these applications, chitosan and soybean-based biomaterials were proposed. These materials were shown to be non cytotoxic and to impair human leukocytes activation in vitro. Thus the goal of this study was to evaluate the in vivo...