2 documents found, page 1 of 1
Akkermansia muciniphila and Parabacteroides distasonis synergistically protect ...
Gaifem, Joana; Mendes-Frias, Ana; Wolter, Mathis; Steimle, Alex; Garzón, Maria Jose; Ubeda, Carles; Nobre, Clarisse; González, Abigail; Pinho, Salomé S.The contribution of the gut microbiome to the balance between homeostasis and inflammation is widely known. Nevertheless, the etiology of inflammatory bowel disease, which is known to be influenced by genetics, immune response, and environmental cues, remains unclear. Unlocking novel players involved in the dictation of a protective gut, namely, in the microbiota component, is therefore crucial to develop novel...
TLR9 activation dampens the early inflammatory response to paracoccidioides bra...
Menino, João Filipe; Saraiva, Margarida; Alves, Ana G. Gomes; Lobo-Silva, Diogo; Sturme, Mark H. J.; Gomes, Jéssica Angélica Rezende; Saraiva, Ana LauraBackground: Paracoccidioides brasiliensis causes paracoccidioidomycosis, one of the most prevalent systemic mycosis in Latin America. Thus, understanding the characteristics of the protective immune response to P. brasiliensis is of interest, as it may reveal targets for disease control. The initiation of the immune response relies on the activation of pattern recognition receptors, among which are TLRs. Both T...