This article provides a comprehensive review of the overlap between autism spectrum disorder and attention-deficit/hyperactivity disorder. It also examines the challenges that these overlaps pose in making accurate differential diagnoses and developing effective treatments.; Este artigo faz uma revisão das sobreposição entre perturbação do espetro do autismo e perturbação de défice de atenção e hiperatividade. ...
The main specific learning disorders are addressed, with regard to their definition, screening, diagnosis and general therapeutic guidance strategies. Particular attention is given to the role of the Pediatrician in early identification of risk factors and clinical manifestations, timely referencing for evaluation by appropriate subspecialists - contributing to a timely diagnosis and early intervention - and ov...
Replacing traditional agricultural ingredients with biotechnologically improved agro-industry by-products in fish diets promotes sustainable aquaculture, reduces production costs and carbon footprint, and promotes a circular economy. Brewers spent grain (BSG) is one such by-product. Solid-state fermentation (SSF) of BSG with Aspergillus ibericus enhances its nutritional value and digestibility for European seab...
This study assessed the effects of dietary inclusion of solid-state fermented (SSF) brewers spent grain (BSG) with Aspergillus ibericus on nutrient and energy digestibility, digestive enzyme activity, and intestinal histomorphology of juvenile European seabass (Dicentrarchus labrax). Five diets (18% crude lipids and 45% crude protein) were formulated, including a control diet (without BSG), two diets with 10% a...
(1) Background: Gastric cancer patients are known to be at a high risk of malnutrition, sarcopenia, and cachexia, and the latter impairs the patient’s nutritional status during their clinical course and also treatment response. A clearer identification of nutrition-related critical points during neoadjuvant treatment for gastric cancer is relevant to managing patient care and predicting clinical outcomes. The a...
Objective: Idiopathic central precocious puberty (iCPP) is common in paediatric endocrinology. Gonadotropin-releasing hormone agonists (GnRHa) are safe, but the effect on final height and the ideal timing for treatment remains controversial. This study aims to assess the effectiveness of GnRHa on growth outcomes in girls with iCPP treated before and after the age of 8 years old. Design and patients: This retros...
O presente trabalho visa evidenciar o processo de co-criação turística de um município localizado no centro de Portugal, Águeda. Desde há 15 anos, o município promove um evento, o AgitÁgueda – Art Festival, integrando concertos musicais, competições desportivas, arte urbana, animação de rua, artesanato, gastronomia e muitas atividades relacionadas com a cultura do município e respetiva cidade. É precisamente no...
Macroalgae are promising ingredients for aquafeeds, but their recalcitrant polysaccharide structure limits their wide use. To disrupt this structure, different physical (ultra-sounds, autoclave, microwaves), chemical (acid, alkaline), and biotechnological (solid-state fermentation, SSF; SSF followed by sequential hydrolysis, SSF-SH) treatments were carried out in Ulva rigida. The chemical composition, morpholog...
The present disclosure relates to an enzyme-rich extract obtained through solid-state fermentation (SSF) of Brewer's Spent Grain (BSG) to be used as a feed additive in animal diets, preferably fish diets. The present patent application also discloses a pre-treatment process of plant feedstuff-based (PF) diets in order to increase the nutrient bioavailability of said diets, thus increasing their nutritional value.