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Integrated Use of Bioaccumulation, Genotoxic, and Haematological Endpoints to A...

Mieiro, CL; Coelho, JP; Reis, AT; Castro, D; Figueira, P; Martinho, F; Pardal, MA; Pereira, E; Pacheco, M; Lopes, CB

Biosorption successfully remediates saline water contaminated with legacy contaminants, but its effects on the health of marine organisms remain unclear. Therefore, our aim was to address this knowledge gap with data on the accumulation ability, as well as the cytogenetic and biochemical effects in turbot (Scophthalmus maximus). To this end, we exposed turbot for seven days to a mixture of remediated metals (Re...


MicroRNAs in lung cancer

Castro, D; Moreira, M; Gouveia, Alexandra; Pozza, D.; De Mello, RA

Lung cancer (LC) is a serious public health problem responsible for the majority of cancer deaths and comorbidities in developed countries. Tobacco smoking is considered the main risk factor for LC; however, only a few smokers will be affected by this cancer. Current screening methods are focused on identifying the early stages of this malignancy. Thus, new data concerning the roles of microRNA alterations in i...


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