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Outbreak of Monkeypox in an STD Clinic in Lisbon

Caldeira, M; Fernandes, C; Neves, J; João, A; Calado, R; Pinto, AR; Borrego, MJ; Cordeiro, R; Machado, J; Pelerito, A; Lopes de Carvalho, I; Vieira, L


Caries prevalence and treatment needs in young people in Portugal: the third na...

Calado, R; Ferreira, CS; Nogueira, P; Melo, P

Objective: To evaluate caries prevalence and dental treatment needs in Portuguese children and teenagers, as well as fluorosis prevalence in 12-year-old children, in order to address public oral health program strategies. Participants: A representative stratified random cluster sample of 3,710 participants of 6, 12, and 18 years old was selected. A questionnaire was applied to determine sociodemographic data an...


Evolution of the Human Immunodeficiency Virus Type 2 Envelope in the First Year...

Rocha, C; Calado, R; Borrego, P; Marcelino, JM; Bártolo, I; Rosado, L; Cavaco-Silva, P; Gomes, P; Família, C; Quintas, A; Skar, H; Leitner, T

Background: Differently from HIV-1, HIV-2 disease progression usually takes decades without antiretroviral therapy and the majority of HIV-2 infected individuals survive as elite controllers with normal CD4+ T cell counts and low or undetectable plasma viral load. Neutralizing antibodies (Nabs) are thought to play a central role in HIV-2 evolution and pathogenesis. However, the dynamic of the Nab response and r...


Baseline Susceptibility of Primary HIV-2 to Entry Inhibitors

Borrego, P; Calado, R; Marcelino, JM; Bártolo, I; Rocha, C; Cavaco-Silva, P; Doroana, M; Antunes, F; Maltez, F; Caixas, U; Barroso, H; Taveira, N

BACKGROUND: The baseline susceptibility of primary HIV-2 to maraviroc (MVC) and other entry inhibitors is currently unknown. METHODS: The susceptibility of 19 HIV-2 isolates obtained from asymptomatic and AIDS patients and seven HIV-1 clinical isolates to the fusion inhibitors enfuvirtide (ENF) and T-1249, and to the coreceptor antagonists AMD3100, TAK-779 and MVC, was measured using a TZM-bl cell-based assay. ...


Papilomatose Respiratória Recorrente

Viegas, V; Calado, R; Marques, A; Cunha Sá, I; Barata, D

A papilomatose respiratória recorrente da criança é uma doença rara, mas potencialmente ameaçadora da vida, e que atinge o trato respiratório com predilecção pela laringe e traqueia. É causada pelo papiloma-vírus humano (tipo 6 e 11). É uma das causas de rouquidão e obstrução da via aérea. É necessário um elevado grau de suspeição diagnóstica, tendo em conta as várias formas de apresentação. Apresenta-se o caso...


Effects of light exposure on the retention of kleptoplastic photosynthetic acti...

Vieira, S; Calado, R; Coelho, H; Serôdio, João

The effects of light exposure on the photosynthetic activity of kleptoplasts were studied in the sacoglossan mollusc Elysia viridis. The photosynthetic activity of ingested chloroplasts was assessed in vivo by non-destructively measuring photophysiological parameters using pulse amplitude modulation (PAM) fluorometry. Animals kept under starvation were exposed to two contrasting light conditions, 30 μmol photon...


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