9 documents found, page 1 of 1

LitKDM2 study: the impact of health Literacy and knowledge about the disease on...

Aims: Diabetes mellitus (DM) is a common chronic disease with serious individual and socioeconomic consequences. Low health literacy (HL) has been associated with higher morbimortality. Health knowledge about DM (HK-DM) may also influence individual health. We aimed to assess HL and HK-DM in patients with type 2 DM and their associations with metabolic control. Methods: Our sample comprised 194 diabetic patient...

Anemia prevalence in women of reproductive age in low- and middle-income countr...

Anemia is a globally widespread condition in women and is associated with reduced economic productivity and increased mortality worldwide. Here we map annual 2000–2018 geospatial estimates of anemia prevalence in women of reproductive age (15–49 years) across 82 low- and middle-income countries (LMICs), stratify anemia by severity and aggregate results to policy-relevant administrative and national levels. Addi...

Mapping inequalities in exclusive breastfeeding in low- and middle-income count...

Exclusive breastfeeding (EBF)-giving infants only breast-milk for the first 6 months of life-is a component of optimal breastfeeding practices effective in preventing child morbidity and mortality. EBF practices are known to vary by population and comparable subnational estimates of prevalence and progress across low- and middle-income countries (LMICs) are required for planning policy and interventions. Here w...

Mapping routine measles vaccination in low- and middle-income countries

Hypoxia and macrophages act in concert towards a beneficial outcome in colon ca...

In colon cancer, the prognostic value of macrophages is controversial, and it is still unknown how hypoxia modulates macrophage–cancer cell crosstalk. To unravel this, co-cultures of human primary macrophages and colon cancer cells were performed at 20% and 1% O2, followed by characterization of both cellular components. Different colon cancer patient cohorts were analyzed for hypoxia and immune markers, and th...

Global, regional, and national age-sex-specific mortality for 282 causes of dea...

Background Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly availa...

Interferon-gamma at the crossroads of tumor immune surveillance or evasion

Interferon-gamma (IFN-¿) is a pleiotropic molecule with associated antiproliferative, pro-apoptotic and antitumor mechanisms. This effector cytokine, often considered as a major effector of immunity, has been used in the treatment of several diseases, despite its adverse effects. Although broad evidence implicating IFN-¿ in tumor immune surveillance, IFN-¿-based therapies undergoing clinical trials have been of...

Accuracy of Faecal Calprotectin and Neutrophil Gelatinase B-associated Lipocali...

BACKGROUND AND AIMS: Mucosal healing and histological remission are different targets for patients with ulcerative colitis, but both rely on an invasive endoscopic procedure. This study aimed to assess faecal calprotectin and neutrophil gelatinase B-associated lipocalin as biomarkers for disease activity in asymptomatic ulcerative colitis patients. METHODS: This was a multicentric cross-sectional study includin...

Teste Rápido VIH e Gravidez

Este estudo pretendeu avaliar o benefício do Teste Rápido VIH na prevenção da transmissão perinatal. Realizou-se um estudo retrospectivo, em que se avaliaram 238 pedidos de Teste Rápido VIH entre 2001 e 2005. Realçaram-se dados relativamente ao pedido de teste, o seu resultado, assim como as medidas profilácticas adoptadas e sua eficácia. Os pedidos incidiram predominantemente em grávidas em trabalho de parto (...