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Phylogenetic Analysis of Hepatitis C Virus Infections in a Large Belgian Cohort...
Christensen, Kasper T.; Pierard, Florian; Bonsall, David; Bowden, Rory; Barnes, Eleanor; Florence, Eric; Ansari, M. Azim; Nguyen, DungFunding Information: This research and Kasper Thorhauge Christensen was funded by grants from the Fonds Wetenschappelijk Onderzoek Vlaanderen (FWO) (G069214, G0B2317N and 1S38819N). Lize Cuypers acknowledges FWO travel grant for a research visit at the University of Oxford (V431117N). Core funding to the Wellcome Centre for Human Genetics was provided by the Wellcome Trust (award 203141/Z/16/Z). The authors ack...
Full-genome next-generation sequencing of hepatitis C virus to assess the accur...
Christensen, Kasper T.; Pierard, Florian; Beuselinck, Kurt; Bonsall, David; Bowden, Rory; Lagrou, Katrien; Nevens, Frederik; Schrooten, YoeriFunding Information: This work and KTC were supported by grants from the Fonds voor Wetenschappelijk Onderzoek Vlaanderen (FWO) ( G069214 , G0B2317N , 1S38819N ). LC acknowledges FWO travel grant for a research visit at University of Oxford ( V431117N ). The authors thank the staff in Oxford in their support of the laboratory work and the donation of the probes used for enrichment of HCV. Publisher Copyright: ©...
Development of HIV Drug Resistance in a Cohort of Adults on First-Line Antiretr...
Sangeda, Raphael Z.; Gómes, Perpétua; Rhee, Soo Yon; Mosha, Fausta; Camacho, Ricardo J.; Van Wijngaerden, Eric; Lyamuya, Eligius F.Publisher Copyright: © 2021 by the authors. Funding R.Z.S. acknowledges the support of the Belgian Technical Cooperation (BTC) for funding his PhD research. Acknowledgments R.Z.S. acknowledges the support of the Belgian Technical Cooperation (BTC) for funding part of this study. A.-M.V. was supported by the Fonds voor Wetenschappelijk Onderzoek Vlaanderen (grant K8.012.12N). Sida funded part of this study under...
Quantifying next generation sequencing sample pre-processing bias in HIV-1 comp...
Vrancken, Bram; Trovão, Nídia Sequeira; Baele, Guy; Van Wijngaerden, Eric; Vandamme, Anne Mieke; van Laethem, Kristel; Lemey, PhilippeGenetic analyses play a central role in infectious disease research. Massively parallelized “mechanical cloning” and sequencing technologies were quickly adopted by HIV researchers in order to broaden the understanding of the clinical importance of minor drug-resistant variants. These efforts have, however, remained largely limited to small genomic regions. The growing need to monitor multiple genome regions fo...