5 documents found, page 1 of 1
Phosphoproteomic analysis of rat neutrophils shows the effect of intestinal isc...
Tahir, Muhammad; Arshid, Samina; Fontes, Belchor; Castro, Mariana S.; Sidoli, Simone; Schwämmle, Veit; Luz, Isabelle Souza; Roepstorff, PeterIntestinal ischemia reperfusion injury (iIRI) is a severe clinical condition presenting high morbidity and mortality worldwide. Some of the systemic consequences of IRI can be prevented by applying ischemic preconditioning (IPC), a series of short ischemia/reperfusion events preceding the major ischemia. Although neutrophils are key players in the pathophysiology of ischemic injuries, neither the dysregulation ...
Paternal resistance training modulates calcaneal tendon proteome in the offspri...
Sousa Neto, Ivo Vieira de; Tibana, Ramires Alsamir; Silva, Leonardo Gomes de Oliveira da; Lira, Eliene Martins de; Prado, Gleyce Pires Gonçalves doThe increase in high-energy dietary intakes is a well-known risk factor for many diseases, and can also negatively impact the tendon. Ancestral lifestyle can mitigate the metabolic harmful effects of offspring exposed to high-fat diet (HF). However, the influence of paternal exercise on molecular pathways associated to offspring tendon remodeling remains to be determined. We investigated the effects of 8 weeks ...
The crude skin secretion of the pepper frog Leptodactylus labyrinthicus is rich...
Libério, Michelle da Silva; Bastos, Izabela Marques Dourado; Pires Junior, Osmindo Rodrigues; Fontes, Wagner; Santana, Jaime Martins dePeptidases are ubiquitous enzymes involved in diverse biological processes. Fragments from bioactive peptides have been found in skin secretions from frogs, and their presence suggests processing by peptidases. Thus, the aim of this work was to characterize the peptidase activity present in the skin secretion of Leptodactylus labyrinthicus. Zymography revealed the presence of three bands of gelatinase activity ...
Evaluation of the effects of ischemic preconditioning on the hematological para...
Tahir, Muhammad; Arshid, Samina; Heimbecker, Ana Maria C.; Castro, Mariana S.; de Souza Montero, Edna Frasson; Fontes, Belchor; Fontes, WagnerOBJECTIVES: Intestinal ischemia/reperfusion often leads to acute lung injury and multiple organ failure. Ischemic preconditioning is protective in nature and reduces tissue injuries in animal and human models. Although hematimetric parameters are widely used as diagnostic tools, there is no report of the influence of intestinal ischemia/reperfusion and ischemic preconditioning on such parameters. We evaluated t...
Dynamics and Conformational Studies of TOAC Spin Labeled Analogues of Ctx(Ile21...
Vicente, Eduardo F. [UNESP]; Basso, Luis Guilherme M.; Cespedes, Graziely F. [UNESP]; Lorenzón, Esteban N. [UNESP]; Castro, Mariana S.Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:28:54Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:43:00Z : No. of bitstreams: 1 2-s2.0-84876038676.pdf: 1769013 bytes, checksum: 558f0e1148e100d956778437f62b5d3e (MD5); Made available in DSpace on 2014-05-27T11:28:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-04-09; Antimicrobial peptides (AMPs) isol...