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Development of a platform to align education and practice: bridging Academia an...

Alves da Costa, Filipa; Martins, Ana Paula; Veiga, Francisco; Ramalhinho, Isabel; Sousa Lobo, José Manuel; Rodrigues, Luís; Granadeiro, Luiza

Limited fitness for practice may result from a mismatch between education and practice. Aiming to meet the common interests of academics and practitioners, the Portuguese Pharmaceutical Society (PPS) developed the Education and Practice Platform (EPP). The EPP includes one representative from each pharmacy faculty, and all Councils of Speciality Boards of Practice. Brainstorming with involved parties enabled sh...


Development of a platform to align education and practice: bridging academia an...

Costa, Filipa Alves da; Martins, Ana Paula; Veiga, Francisco; Ramalhinho, Isabel; Lobo, José Manuel Sousa; Rodrigues, Luís; Granadeiro, Luiza

Limited fitness for practice may result from a mismatch between education and practice. Aiming to meet the common interests of academics and practitioners, the Portuguese Pharmaceutical Society (PPS) developed the Education and Practice Platform (EPP). The EPP includes one representative from each pharmacy faculty, and all Councils of Speciality Boards of Practice. Brainstorming with involved parties enabled sh...


Development of a platform to align education and practice: bridging academia an...

Alves da Costa, Filipa; Martins, Ana Paula; Veiga, Francisco; Ramalhinho, Isabel; Sousa Lobo, José Manuel; Rodrigues, Luís; Granadeiro, Luiza

Limited fitness for practice may result from a mismatch between education and practice. Aiming to meet the common interests of academics and practitioners, the Portuguese Pharmaceutical Society (PPS) developed the Education and Practice Platform (EPP). The EPP includes one representative from each pharmacy faculty, and all Councils of Speciality Boards of Practice. Brainstorming with involved parties enabled sh...


Stress oxidativo e defesas antioxidantes: uma revisão pedagógica

Fernandes, Ana Sofia; Castro, Matilde; Oliveira, Nuno Guerreiro

Nos últimos anos tem havido um interesse crescente pelos efeitos do stress oxidativo, e muitas evidências científicas indicam que este está envolvido em diversos fenómenos patológicos. O presente artigo pretende rever os conceitos de stress oxidativo e defesas antioxidantes, permitindo introduzir os profissionais e alunos da área da saúde nesta temática. Assim, são abordadas as principais vias de formação de es...


Antibioterapia local para tratamento de infecções em implantes ortopédicos

Bettencourt, Ana; Duarte, Aida; Pinto, Pedro; Castro, Matilde; Monteiro, Jacinto

Antibioterapia local para tratamento de infecções ortopédicas.


Oxidative injury in V79 Chinese hamster cells: protective

Fernandes, Ana S.; Serejo, João; Gaspar, Jorge; Cabral, Fátima; Bettencourt, Ana F.; Rueff, José; Castro, Matilde; Costa, Judite; Oliveira, Nuno G.

Oxidative cell injury could be induced by different reactive oxygen species (ROS) operating in multiple pathways. The present work is focused on three different models of oxidative stress: the xanthine/xanthine oxidase system (XXO), an extracellular superoxide anion generator; tert-butylhydroperoxide (TBHP), an analogue of lipid hydroperoxides; and doxorubicin (Dox), an anticancer drug. Superoxide and peroxyl r...


Total and organic mercury, selenium and alpha-tocopherol in some deep-water fis...

Afonso, Claudia; Lourenco, Helena M.; Pereira, Catia; Martins, Maria F.; Carvalho, Maria L.; Castro, Matilde; Nunes, Maria L.

BACKGROUND: Mercury is a well-known toxic element present in seafood. Nevertheless some antioxidants, like selenium, as an integral component of the enzyme glutathione peroxidase, and alpha-tocopherol having a protective role against it, are present as well. The purpose of this study was to evaluate the levels of total mercury (Hg-T), organic mercury (Hg-Org), Se and alpha-tocopherol in some adult deep-water fi...


Lipid composition and nutritional value of some meats with Protected Designatio...

Prates, José A. M.; Ribeiro, Verónica; Quaresma, Mário; Lourenço, Marta; Martins, Susana; Alves, Susana; Portugal, Ana; Castro, Matilde

The aim of this work was to characterise and compare the lipid cQmposition (lípid and eholcsterol contents, fatty acid composition and conjugated linoleie acid isomers) and nutritiona! value (PUFA/SFA and n-6/n-3 ratios) of four Portuguese mea!s with Protceted Designation of Origin (POO; Camalentejana-PDO beel: Mertolenga-POO beef, Barrosã-POO veal and Arouquesa-POO veal), in 1\\'0 distinct slaughter seasoos (e...


Evaluation of the protective effect of MnTMPyP on the cytotoxicity induced by d...

Fernandes, Ana Sofia; Gaspar, Jorge; Cabral, M. Fatima; Bettencourt, Ana F.; Caneiras, Catla; Rueff, Jose; Castro, Matilde; Costa, Judite


Macrocyclic copper(II) complexes

Fernandes, Ana S.; Gaspar, Jorge; Cabral, M. Fatima; Caneiras, Catia; Guedes, Rita; Rueff, Jose; Castro, Matilde; Costa, Judite; Oliveira, Nuno G.

Synthetic superoxide dismutase mimetics have emerged as a potential novel class of drugs for the treatment of oxidative stress related diseases. Among these agents, metal complexes with macrocyclic ligands constitute an important group. In this work we synthesized five macrocyclic copper(II) complexes and evaluated their ability to scavenge the superoxide anions generated by the xanthine-xanthine oxidase system...


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