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Bioinformatic tools for exploring the SUMO gene network: An update

Castro, Pedro Humberto; Santos, Miguel Ângelo; Magalhães, Alexandre Papadopoulos; Tavares, R. M.; Azevedo, Herlander

Plant sumoylation research has seen significant advances in recent years, particularly since high-throughput proteomic strategies have enabled the discovery of more than one thousand SUMO targets. In the present chapter, we update the previously reported SUMO (small ubiquitin-related modifier) gene network (SGN) to its v4 iteration. SGN is a curated assembly of Arabidopsis thaliana genes that have been function...


Integrative transcriptomic and metabolomic approaches to unravel the resistance...

Guerra-Guimarães, Leonor; Azevedo, Herlander; Diniz, Inês; Carrera, Jéfyne; Guedes, Fernanda A.F.; Pinheiro, Carla; Azinheira, Helena Gil


Characterization of the transcriptional signatures associated with resistance a...

Azevedo, Herlander; Diniz, Inês; Figueiredo, Andreia; Guedes, Fernanda Alves Freitas; Sebastiana, Mónica Guita; Azinheira, Helena Gil; Barros, Danielle

Coffee leaf rust (CLR), a disease caused by the biotrophic fungus Hemileia vastatrix (Hv), is the main threat to the worldwide production of Arabica coffee. The gradual breakdown of resistance in coffee varieties in the last years has highlighted the need for novel sources of resistance to CLR. This work aimed to unveil the cellular and molecular resistance profile of the Kawisari hybrid (C. arabica x C. liberi...


SUMO E3 ligase SIZ1 connects sumoylation and reactive oxygen species homeostasi...

Castro, Pedro Humberto; Couto, Daniel; Santos, Miguel Angelo; Freitas, Sara; Lourenco, Tiago; Dias, Eva; Huguet, Stephanie; da Silva, Jorge Marques

The ubiquitin-like modifying peptide SMALL UBIQUITIN-LIKE MODIFIER (SUMO) has become a known modulator of the plant response to multiple environmental stimuli. A common feature of many of these external stresses is the production of reactive oxygen species (ROS). Taking into account that SUMO conjugates rapidly accumulate in response to an external oxidative stimulus, it is likely that ROS and sumoylation conve...


RNA-Seq and gene network analysis uncover activation of an ABA-dependent signal...

Magalhães, Alexandre P.; Verde, Nuno; Reis, Francisca; Martins, Inês; Costa, Daniela; Lino-Neto, T.; Castro, Pedro Humberto; Tavares, R. M.

Quercus suber (cork oak) is a West Mediterranean species of key economic interest, being extensively explored for its ability to generate cork. Like other Mediterranean plants, Q. suber is significantly threatened by climatic changes, imposing the need to quickly understand its physiological and molecular adaptability to drought stress imposition. In the present report, we uncovered the differential transcripto...


Proteases associated with post-translational modification act as modulators of ...

Castro, Pedro Humberto; Couto, Daniel; Tavares, R. M.; Bejarano, Eduardo R.; Azevedo, Herlânder


Analysis of ROS production and homeostasis in an arabidopsis thaliana knockout ...

Couto, Daniel; Castro, Pedro Humberto; Dias, Eva; Bejarano, Eduardo R.; Tavares, R. M.; Azevedo, Herlânder


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