5 documents found, page 1 of 1
Comparative genomics of two pseudomonas aeruginosa clinical isolates to elucida...
Castro, Pedro Soares; Marques, Diana; Demyanchuk, Sergey; Faustino, A.; Santos, P. M.Recently, we have set a collaboration with Hospital de Braga, located in the North of Portugal, that handles over 600 P. aeruginosa isolates per year, aiming to rouse a holistic research approach to provide relevant information and tools to the clinicians to circumvent the multi-resistance phenomena in P. aeruginosa. Since then, we have set procedures aiming a systematic phenotypic characterization of the clini...
Towards the metabolic engineering of myrcene pathway of pseudomonas sp. M1 usin...
Castro, Pedro Soares; Santos, P. M.Pseudomonas sp. M1, isolated from the Rhine River, is able to utilize a large variety of toxic and/or recalcitrant compounds as sole carbon and energy sources, including phenols, benzene and monoterpenes like myrcene [1-3]. Therefore, M1 strain holds great potential as a source of novel biomolecules and cell factories for various biotechnological applications namely in biocatalysis, biosensors, bioremediation a...
Insights into the accessory genome of two pseudomonas aeruginosa clinical isola...
Castro, Pedro Soares; Marques, Diana; Demyanchuk, Sergey; Faustino, A.; Santos, P. M.Recently, we have set a collaboration with Hospital de Braga, located in the North of Portugal, that handles over 600 P. aeruginosa isolates per year, aiming to rouse a holistic research approach to provide relevant information and tools to the clinicians to circumvent the multi-resistance phenomena in P. aeruginosa. Since then, we have set procedures aiming a systematic phenotypic characterization of the clini...
Draft genome sequences of two pseudomonas aeruginosa clinical isolates with dif...
Castro, Pedro Soares; Marques, Diana; Demyanchuk, S.; Faustino, A.; Santos, P. M.Pseudomonas aeruginosa is a primary cause of opportunistic infections. We have sequenced and annotated the genomes of two P. aeruginosa clinical isolates evidencing different antibiotic susceptibilities. Registered differences in the composition of their accessory genomes may provide clues on P. aeruginosa strategies to thrive in different environments like infection loci.; PTDC/EBB-BIO/104980/2008, Foundation ...
An integrated omic approach towards the metabolic engineering of myrcene pathwa...
Castro, Pedro Soares; Santos, P. M.Best Poster Award; Pseudomonas sp. M1 is able to utilize a large variety of toxic and/or recalcitrant compounds as sole carbon and energy sources, including phenols, benzene and monoterpenes like myrcene [1-3]. Therefore, M1 strain holds great potential as a source of novel biomolecules and cell factories for various biotechnological applications namely in biocatalysis, biosensors, bioremediation and biomedicin...