3 documents found, page 1 of 1
A novel vasorelaxant lectin purified from seeds of Clathrotropis nitida: Partia...
Alves, Ana Cecília; Vasconcelos, Mayron Alves de; Santiago, Mayara Quiroz; Pinto-Junior, Vanir Reis; Osterne, Vinicius José SilvaA novel lectin from seeds of Clathrotropis nitida (CNA) was purified and characterized. CNA is a glycoprotein containing approximately 3.3% carbohydrates in its structure. CNA promoted intense agglutination of rabbit erythrocytes, which was inhibited by galactosides and porcine stomach mucin (PSM). The lectin maintained its hemagglutinating activity after incubation in a wide range of temperatures (30-60 °C) an...
Efeitos da galactomanana de Cyamopsis tetragonolobus na osteoartrite induzida p...
Castro, Rondinelle RibeiroUsing the osteoarthritis (OA) model induced by anterior cruciate ligament transection (ACLT) in rats, we have demonstred that guar gum (GG), a galactomannan extracted from Cyamopsis tetragonolobus seeds, displays analgesic activity similar to Hylan G-F 20, a hyaluronate derivate used as local therapy in human OA. In the same model, we objective to develop a parametric biochemical method for joint lesion evaluat...
Hiperalgesia articular no modelo de osteoartrite por transecção do ligamento cr...
Castro, Rondinelle RibeiroAnimal models have been employed for the study of osteoarthritis (OA), but the articular hyperalgesia has received little attention. In this study, we standardized a method to study hyperalgesia in an OA model in rats, through the anterior cruciate ligament transection (ACLT), as well as the role of Nitric Oxide (NO). High molecular weight (MW) polysaccharides, such as Hylan G-F 20, as a gel preparation, have b...