10 documents found, page 1 of 1
Biocompatibility and biodegradation analysis of Nile Tilapia gelatin and apatit...
Sousa,Efigênia Maria de; Melo,Edla Freire de; Ribeiro,Hálisson Lucas; Feitosa,Judith Pessoa de Andrade; Souza-Filho,Men de Sá Moreira deABSTRACT Fish farming by-products could represent large-scale raw materials for xenogeneic implants that could be used for bone regeneration. The objective of this research was to analyze the biocompatibility and biodegradation of gelatin (G) and apatite (A) membranes from Nile tilapia. Adult male Swiss mice underwent subcutaneous implantation of biocomposites derived from skins and scales in different concentr...
Mental health in adolescence: Elaboration and validation of an educational tech...
Rocha,Sibele Pontes; Farias,Quiteria Larissa Teodoro; Vasconcelos,Maristela Inês Osawa; Lopes,Stella Maris Brum; Castro-Silva,Igor IucoABSTRACT Objective: to build and validate the appearance of a digital educational technology to promote the mental health of school adolescents. Methods: methodological study, which included the elaboration and validation of the “Conect@dos com a S@ude” online course based on the Galvis-Panqueva methodological framework. The elaboration was based on a literature review and followed the Theory of Meaningful Lear...
Poultry by-products as source of collagen, nanokeratin and bioapatite for biome...
Souza,Francisco Fábio Pereira de; Cavalcante,Fabio Lima; Castro-Silva,Igor Iuco; Silva,André Luis Coelho da; Souza Filho,Men de Sá Moreira deABSTRACT Xenogeneic sources are attractive for the development of natural and sustainable biomaterials. The objective of this study was to extract and perform the physicochemical and biological characterization of poultry collagen (G1), nanokeratin (G2) and bioapatite (G3). The test materials were analyzed through SEM, FTIR, TGA, EDS and DRX. The in vivo biocompatibility and biodegradation of the materials were...
Análise inicial da correlação espacial entre a incidência de COVID-19 e o desen...
Maciel,Jacques Antonio Cavalcante; Castro-Silva,Igor Iuco; Farias,Mariana Ramalho deRESUMO: Objetivo: Analisar a distribuição espacial da incidência de Covid-19 e sua correlação com o índice de desenvolvimento humano municipal (IDHM) dos municípios do Ceará. Métodos: Trata-se de um estudo ecológico com dados recuperados da 15ª e da 19ª semana epidemiológica do ano de 2020 utilizando como variáveis o IDHM e o coeficiente de incidência de Covid-19 para cada município. Foi analisada a correlação ...
Panorama de pesquisas com seres humanos sobre covid-19 no Brasil
Castro-Silva,Igor Iuco; Maciel,Jacques Antonio CavalcanteResumo A pandemia de covid-19 desafia instituições de pesquisa pela urgência de responder à morbimortalidade provocada pelo vírus. O objetivo deste estudo foi traçar panorama das pesquisas com humanos sobre essa doença no primeiro trimestre de 2020 no Brasil. Dados oficiais de saúde da população e de protocolos de pesquisa sobre a covid-19, distribuídos por estados brasileiros, subsidiaram a análise temporal. H...
Immunohistochemical evaluation of MMP-2, MMP-9 and CD31/microvascular density i...
Monteiro-Amado,Flávio; Castro-Silva,Igor Iuco; Lima,Cristina Jardelino de; Soares,Fernando Augusto; Kowalski,Luiz Paulo; Granjeiro,José MauroThe aim of this study was to evaluate the immunoexpression of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth and to correlate the results with demographic, survival, clinical (TNM staging) and histopathological variables (tumor grade, perineural invasion, embolization and bone invasion). Data from medical records and diagnoses of 41 patients were reviewed. Hist...
Pérola de esmalte: epidemiologia, morfopatogênese e relevância na clínica odont...
Castro-Silva,Igor Iuco; Azevedo,Fábio Lopes de; Otero,DanielINTRODUÇÃO: Distúrbios da odontogênese geram anomalias dentárias com relevância diagnóstica e terapêutica. OBJETIVO: O presente artigo teve como objetivos fazer uma revisão sistemática sobre a pérola de esmalte e discutir seu processo formativo, bem como a sua significância na clínica odontológica. MATERIAL E MÉTODO: Três bancos de dados eletrônicos (Pubmed, Cochrane e Biblioteca Virtual em Saúde) foram usados ...
Isolation of human umbilical cord blood-derived osteoprogenitor cells: a promis...
Castro-Silva,Igor Iuco; Castro,Letícia de Oliveira; Machado,Janaína José dos Santos; Nicola,Maria Helena Alves; Granjeiro,José MauroABSTRACT Objective: The aim of this study was to evaluate the osteogenic potential of human umbilical cord blood-derived osteoprogenitor cells and to prove its applicability as a promising candidate for cell-based therapeutics for bone repair. Methods: Primary cultures of human umbilical blood cord adherent cells were expanded in vitro until passage 2 and seeded for osteodifferentiation study. Morphological (li...
Repair of critical-size defects with autogenous periosteum-derived cells combin...
Paulo,Anderson de Oliveira; Castro-Silva,Igor Iuco; Oliveira,Davi Ferreira de; Machado,Manoel Eduardo de Lima; Bonetti-Filho,IdomeoThe aim of this study was to evaluate the bone repair using autogenous periosteum-derived cells (PDC) and bovine anorganic apatite and collagen (HA-COL). PDC from Wistar rats (n=10) were seeded on HA-COL discs and subjected to osteoinduction during 6 days. Critical-size defects in rat calvarias were treated with blood clot (G1), autogenous bone (G2), HA-COL (G3) and HA-COL combined with PDC (G4) (n=40), and the...
Porcine peritoneum as source of biocompatible collagen in mice
Jardelino,Cristina; Takamori,Esther Rieko; Hermida,Luiz Felipe; Lenharo,Ariel; Castro-Silva,Igor Iuco; Granjeiro,Jose MauroPURPOSE: To investigate the biocompatibility and biodegradability of a membrane made from porcine peritoneum. METHODS: The membrane (5x5 mm) was inserted in the subcutaneous tissue on the back of 15 mice, which were killed after 1, 3 and 9 weeks (ISO 10993-6). The cellular components of the inflammatory response and degradation of the membrane were analyzed in hematoxylin-eosin-stained histological sections. RE...