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Gold nanoparticles: a promising next-generation tool for breast cancer photothe...

Ferreira-Gonçalves, Tânia; Costa, Eduardo; Coelho, João; Gaspar, Maria Manuela; Ascensão, Lia; Ferreira-Santos, Pedro; Faísca, Pedro; Figueiredo, Isabel

AuNPs show suitable mean sizes and maximum absorbance peaks to be used for PTT when locally administered. AuNPs show no toxicity either in breast cancer cell lines or red blood cells. Laser irradiation proved to be safe when applied alone. Combining EGF-conjugated AuNPs with laser irradiation resulted in a reduction of 33% in MCF-7 cells viability. The animal model was successfully developed (all animals develo...

Date: 2025   |   Origin: Repositório Científico da Universidade de Évora
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