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Combination of gold nanoparticles with near-infrared light as an alternative ap...

Lopes, Joana; Rodrigues, Carla M; Godinho-Santos, Ana; Coelho, João M. P.; Cabaço, Luís C.; Barral, Duarte C.; Faísca, Pedro; Catarino, José

Copyright © 2024. Published by Elsevier B.V.; Melanoma is the most aggressive type of skin cancer and recently approved drugs are often associated with resistance and significant adverse effects. Therefore, the design of more effective and safe options remains imperative. Photothermal therapy (PTT) using gold nanoparticles (AuNPs) presents a promising and innovative approach. In this work, the efficacy of combi...


Safety of Gold Nanoparticles

Lopes, Joana; Ferreira-Gonçalves, Tânia; Ascensão, Lia; Viana, Ana S.; Carvalho, Lina; Catarino, José; Faísca, Pedro; Oliva, Abel

Funding Information: The authors acknowledge Fundação para a Ciência e a Tecnologia (FCT) for financial support through Projects UIDB/00645/2020, UIDB/04138/2020, UIDP/04138/2020, PTDC/BTM-MAT/31794/2017, and PTDC/QUI-QIN/0586/2020, as well as PhD fellowships SFRH/BD/148044/2019 and SFRH/BD/147306/2019. The authors are also thankful for the financial support to CESAM by FCT/MCTES (UIDP/50017/2020+UIDB/50017/202...


Biological Thermal Performance of Organic and Inorganic Aerogels as Patches for...

Ferreira-Gonçalves, Tânia; Iglesias-Mejuto, Ana; Linhares, Teresa; Coelho, João M. P.; Vieira, Pedro; Faísca, Pedro; Catarino, José; Pinto, Pedro

Funding Information: The authors would like to thank to Fundação para a Ciência e a Tecnologia (FCT) for the essential financial support under project reference UIDB/EQU/00102/2020, and to MICINN [PID2020-120010RB-I00], Agencia Estatal de Investigación [AEI] and FEDER funds. A.I.-M. also acknowledges to Xunta de Galicia for her predoctoral research fellowship [ED481A-2020/104]. Funding Information: This work wa...


Gold-based nanoplataform for the treatment of anaplastic thyroid carcinoma

Amaral, Mariana; Charmier, Adília J.; Afonso, Ricardo A.; Catarino, José; Faísca, Pedro; Carvalho, Lina; Ascensão, Lia; Coelho, João M.P.

Funding: Authors gratefully acknowledge Fundação para a Ciência e a Tecnologia (FCT) through projects UIDB/00645/2020, UIDB/04138/2020, PTDC/MED-QUI/31721/2017, UIDP/04138/2020 and Lusófona University, ULHT. Authors are also thankful to FCT/MCTES for the financial support to CESAM (UIDP/50017/2020, UIDB/50017/2020), through national funds.; Anaplastic thyroid carcinoma (ATC) is a very rare subtype of thyroid ca...


How can biomolecules improve mucoadhesion of oral insulin? A comprehensive insi...

Amaral, Mariana; Martins, Ana Sofia; Catarino, José; Faísca, Pedro; Kumar, Pradeep; Pinto, João F.; Pinto, Rui; Correia, Isabel; Ascensão, Lia

Funding: Supported in part by UID/DTP/04138/2019 from FCT, Portugal and DREAMS (ULHT). SEM analysis was funded by FCT/MCTES for the financial support to CESAM (UIDP/50017/2020+UIDB/50017/2020), through national funds.; Currently, insulin can only be administered through the subcutaneous route. Due to the flaws associated with this route, it is of interest to orally deliver this drug. However, insulin delivered ...


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