This study investigates alterations at the level of the genome and at level of gene expression in dogs with Canine Cutaneous Histiocytoma (CCH). CCH is a benign tumor originating from Langerhans cells (LC), remarkably like pediatric LC Histiocytoma. While CCH is highly prevalent in young dogs, it spontaneously regresses within 2–3 mo, providing a unique opportunity to study immune-mediated tumor control. Unlike...
Mast cell tumors (MCT) are among the most common neoplasia in dogs, representing up to 21 % of skin tumors. However, etiology and risk factors for its development remain unclear. This study aimed to reduce this knowledge gap by comprehensively analyzing 905 MCT cases diagnosed in Portugal between 2019 and 2021, using descriptive and inferential analyses. Most tumors affected the skin, with 69.9 % and 21.2 % cla...
The animal cancer burden is essential for the translational value of companion animals in comparative oncology. The present work aims to describe, analyze, and compare frequencies and associations of tumors in dogs and cats based on the Animal Cancer Registry created by Vet-OncoNet. With 9079 registries, regarding 2019 and 2020, 81% (n = 7355) belonged to dogs. In comparison, cats have a general one-year right ...
Analysis of canine and feline tumor malignancy data can help clinicians identify high-risk patients and make more accurate decisions. Based on a sample of 16,272 cancer records, including 3266 cats and 13,006 dogs, collected from January 2019 to December 2021 in the Vet-OncoNet Network database, this study aimed to compare the tumor malignancy profile between cats and dogs, considering animal-related factors (s...
INTRODUCTION: Delayed type Ia endoleaks are often associated with proximal extension of the aneurysmal degeneration to the juxtarenal aortic segment. Endovascular treatment of type Ia endoleaks secondary to aortic neck dilatation can raise many technical challenges related to the previous implanted stent graft. CASE REPORT: The authors present a clinical case of an 84 year-old man, with a past medical history o...
INTRODUCTION: Endovascular aneurysm repair (EVAR) offers signifcant advantages on aneurysm treatment. However, the management of EVAR complications or failure often results in complex surgical approaches, sometimes requiring graft explantation which remains a major challenge and one associated with a high morbidity and mortality. The purpose of this study is to review our contemporary institutional experience w...
INTRODUÇÃO: Nas últimas duas décadas, a abordagem de tratamento de aneurisma da aorta abdominal (AAA) mudou drasticamente de cirurgia aberta para cirurgia endovascular. A diminuição de cirurgia de AAA convencional , open aneurysm repair (OAR), levanta preocupações relativamente à competência dos futuros cirurgiões vasculares para executar este procedimento complexo e de alto risco. O principal objetivo deste es...
INTRODUCTION: Phlegmasia cerulea (PC) is a severe form of deep vein thrombosis. In the setting of massive venous thrombosis and severe ischemia, catheter-directed thrombolysis (CDT) or trombectomy is mandatory. We report three cases of women with PC managed with venous thrombectomy after failure of CDT. CASE REPORTS: 1: 20 years-old, with recent intake of oral contraceptive, referred with acute onset of limb sw...
Introdução: O elevado número de procedimentos vasculares percutâneos resulta num aumento das complicações relacionadas com o acesso vascular. A mais frequente é o falso aneurisma (FA), cuja intervenção de primeira linha é atualmente a injeção eco-guiada de trombina humana (IETH). Métodos: Estudo observacional retrospetivo realizado através da consulta de processos clínicos dos doentes submetidos a IETH por FA f...
Introdução: A incidência de isquemia aguda renal é baixa. A experiência publicada do seu tratamento cirúrgico resume-se a séries de casos e não há indicações bem definidas para a revascularização renal em caso de isquemia aguda. Métodos: Estudo observacional retrospetivo realizado com base na consulta de processos clínicos de doentes submetidos a revascularização de artéria renal por isquemia aguda renal, num h...