2 documents found, page 1 of 1
Recrudescent Plasmodium berghei from Pregnant Mice Displays Enhanced Binding to...
Marinho, Claudio R. F.; Neres, Rita; Epiphanio, Sabrina; Goncalves, Ligia A.; Catarino, Manuela Beirao; Penha-Goncalves, CarlosPregnancy-associated malaria (PAM) is associated with placenta pathology and poor pregnancy outcome but the mechanisms that control the malaria parasite expansion in pregnancy are still poorly understood and not amenable for study in human subjects. Here, we used a set of new tools to re-visit an experimental mouse model of pregnancy-induced malaria recrudescence, BALB/c with chronic Plasmodium berghei infectio...
Pregnancy Outcome and Placenta Pathology in Plasmodium berghei ANKA Infected Mi...
Neres, Rita; Marinho, Claudio R. F.; Goncalves, Ligia A.; Catarino, Manuela Beirao; Penha-Goncalves, CarlosPregnancy-associated malaria (PAM) is expressed in a range of clinical complications that include increased disease severity in pregnant women, decreased fetal viability, intra-uterine growth retardation, low birth weight and infant mortality. The physiopathology of malaria in pregnancy is difficult to scrutinize and attempts were made in the past to use animal models for pregnancy malaria studies. Here, we des...