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Causal pathways from enteropathogens to environmental enteropathy : findings fr...

Kosek, Margaret N.; Ahmed, Tahmeed; Bhutta, Zulfiquar; Caulfield, Laura; Guerrant, Richard; Houpt, Eric; Kang, Gagandeep; Lee, Gwenyth; Lima, Aldo

Background: Environmentalenteropathy (EE),the adverseimpact offrequent and numerous entericinfections on the gut resulting in a state of persistent immune activation and altered permeability, has been proposed as a key determinant of growth failure in children in low- and middle-income populations. A theory-driven systems model to critically evaluate pathways through which enteropathogens, gut permeability, and...

Date: 2017   |   Origin: Oasisbr
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