8 documents found, page 1 of 1
MicroRNAs as potential biomarkers of response to modified Atkins diet in treatm...
Samões, Raquel; Cavalheiro, Ana; Santos, Cristina; Lopes, Joana; Teixeira, Catarina; Tavares, Maria Manuel; Carvalho, Cláudia; Lemos, CarolinaBackground: Accurate predictors of response to modified Atkins diet (MAD) are needed. MicroRNAs are potential biomarkers in epilepsy. This study aimed to explore the value of circulating miR-146a, miR-155, miR-22, miR-21 and miR-134 levels in predicting response to MAD. Methods: Patients who completed 3 months of MAD were selected from a prospective cohort of adults with DRE followed in a specialized MAD outpat...
Sleep disturbances in Parkinson's disease are associated with central parkinson...
Vila-Chã, N.; Cavaco, Sara; Mendes, A.; Gonçalves, A.; Moreira, I.; Fernandes, J.; Damásio, Joana; Azevedo, Luís; Castro-Lopes, JoseIntroduction: Sleep disturbances and pain are common non-motor symptoms in Parkinson's disease (PD). This study aimed to explore the association between these two symptoms in a cohort of patients with PD. Materials and methods: The Parkinson's Disease Sleep Scale (PDSS-2) was used to identify sleep disturbances in a series of 229 PD patients. The identification and characterization of pain was performed by a se...
Proinflammatory and anti-inflammatory cytokines in the CSF of patients with Alz...
Taipa, Ricardo; das Neves, Sofia P.; Sousa, Ana L.; Fernandes, Joana; Pinto, Claudia; Correia, Ana P.; Santos, Ernestina; Pinto, Pedro S.Cumulative data suggest that neuroinflammation plays a prominent role in Alzheimer's disease (AD) pathogenesis. The purpose of this work was to assess if patients with AD present a specific cerebrospinal fluid (CSF) cytokine profile and if it correlates to disease progression. We determined the levels of 27 cytokines in CSF of patients with AD and compared them with patients with frontotemporal dementia and non...
Medir a validade da avaliação neuropsicológica em doentes com esclerose múltipl...
Ferreira, Inês; Gomes, Filomena; Moreira, Inês; Silva, Ana; Cavaco, Sara
Dor na doença de Parkinson
Vila-Chã, Nuno; Gonçalves, Alexandra; Moreira, Inês; Mendes, Alexandre; Azevedo, LF; Cavaco, Sara; Castro-Lopes, JM
Scanning Patterns of Faces do not Explain Impaired Emotion Recognition in Hunti...
van Asselen, Marieke; Júlio, Filipa; Januário, Cristina; Campos, Elzbieta Bobrowicz; Almeida, Inês; Cavaco, Sara; Castelo-Branco, MiguelIn the current study, we aimed to investigate the emotion recognition impairment in Huntington's disease (HD) patients and define whether this deficit is caused by impaired scanning patterns of the face. To achieve this goal, we recorded eye movements during a two-alternative forced-choice emotion recognition task. HD patients in pre-symptomatic (n = 16) and symptomatic (n = 9) disease stages were tested and th...
Auditory Verbal Learning Test: Normative data for ages 21 through 65
Cavaco, Sara; Pinto, Cláudia; Gonçalves, Alexandra; Gomes, Filomena; Pereira, Alexandra; Malaquias, CristinaThe Auditory Verbal Learning Test (AVLT) is one of the most widely used neuropsychological instruments in clinical practice and cognitive research. We adapted the AVLT to the Portuguese population and collected normative data. The sample consisted of 287 subjects without evidence or history of neurological or psychiatric disturbances, ranging in age from 21 through 65. Both free recall and delayed recognition w...
Trail Making Test: Normative data for ages 21 through 65
Cavaco, Sara; Pinto, Cláudia; Gonçalves, Alexandra; Gomes, Filomena; Pereira, Alexandra; Malaquias, CristinaThe Trail Making Test (TMT) is one of the most widely used neuropsychological instruments in clinical practice and cognitive research. We adapted the TMT to the Portuguese population and collected normative data. The sample consisted of 416 subjects without evidence or history of neurological or psychiatric disturbances, ranging in age from 21 through 65, with 4 or more years of education. The collected normati...