The integration of insects into sustainable food and feed chains demands a robust evaluation of their capacity to accumulate and eliminate contaminants. Understanding these dynamics is fundamental to ensuring consumer safety and supporting the development of regulatory standards for insect-derived products. This study assessed the bioaccumulation and depuration kinetics of metal(loid)s (As, Cd, Pb) and mycotoxi...
Many previous studies have investigated the economic production of polyhydroxyalkanoates (PHA) by natural microbiomes. A key underlying strategy is the feast and famine (F/F) feeding regimen for bacteria selection. For this purpose, a sequencing batch reactor (SBR) is commonly operated in a sequence of F/F cycles until an evolved microbiome is attained with high PHA storage capacity. The effectiveness of this p...
Hybrid modeling is gaining prominence in various industrial sectors because it offers a flexible balance between mechanistic and data-driven modeling. However, the adoption of such hybrid modeling techniques has been rather limited. Only few expert researchers using in-house tools have technical background and skills to develop such hybrid models worldwide. Additionally, freely available and user-friendly softw...
This work focuses on predicting material parameters that describe the plastic behaviour of metallic sheets using the XGBoost machine learning algorithm, with a dual focus on the influence of data filtering and data noise. A dataset was populated with finite element simulation results of cruciform tensile tests, including strain field data during the test. Different noise levels were added to the strain-related ...
Hybrid modeling combining First-Principles with Machine Learning (ML) is becoming a pivot-al methodology for Biopharma 4.0 enactment. Combining ML with prior knowledge general-ly improves the model predictive power and model transparency while reducing the amount of data for process development. However, most previous studies pursued a shallow hybrid modeling approach based on three-layered Feedforward Neural N...
Considering the global food crisis and the pressing issue of waste generation, sustainable solutions for food demand are crucial. Insects have emerged as a promising protein source for food and feed due to their efficient bioconversion capacity and ability to utilize nonvaluable products. However, ensuring the safety of insects for food and feed is essential. This study aims to comprehensively evaluate the upta...
Congenital diaphragmatic hernia due to diaphragmatic agenesis is extremely rare. We report the case of a 53-year-old female patient with a congenital right diaphragmatic hernia due to a right hemidiaphragm agenesia diagnosed in the context of acute intrathoracic cholecystitis. She was admitted to the Emergency Department for diffuse abdominal pain, nausea and vomiting with 2 days of evolution. Thoracic and abdo...
The three films analysed in this research—Recollections of the Yellow House (1989), God’s Comedy (1995), and The Spousals of God (1999)—are built from a set of citations taken from different contexts. With those, João César Monteiro forms the fictional world where João de Deus (interpreted by the director) lives. As with many other components of these works, the music is taken from pre-existing pieces that a...
Conjunto de artigos resultantes de revisão cega por pares dentro da temática dos Riscos Psicossociais e áreas relacionadas
Cutaneous metastases from primary gastric carcinoma are uncommon, generally occur late in the course of the disease and have a poor prognosis. We report a long-term survival of a patient with cutaneous metastases from a gastric carcinoma. A 56-year-old patient, previously diagnosed with a poorly differentiated signet-ring cell gastric carcinoma staged as ypT3N3aM0, who underwent total gastrectomy with Roux-en-y...