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Role of NMDA receptors in the trigeminal pathway, and the modulatory effect of ...

Cavalcante, André L. C.; Siqueira, Rafaelly M. P.; Araujo, Joana C. B.; Gondim, Delane V.; Quetz, Josiane S.; Havt, Alexandre; Lima, Aldo A. M.

Temporomandibular joint (TMJ) arthritis is a common cause of orofacial pain. In the present study, the modulatory effects of N-methyl-D-aspartate receptors (NMDA-Rs) and magnesium were investigated in TMJ arthritis hypernociception. Male Wistar rats received an intra-articular injection of carrageenan (Cg) in the TMJ, and mechanical hypernociception was measured. The NMDA-R antagonist, MK-801, and magnesium chl...

Date: 2014   |   Origin: Oasisbr

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