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Molecular and cellular biomarkers of COVID-19 prognosis : protocol for the pros...

Kurizky, Patricia Shu; Nóbrega, Otávio T.; Soares, Alexandre Anderson de Sousa Munhoz; Aires, Rodrigo Barbosa; Albuquerque, Cleandro Pires de

Background: Since the beginning of the COVID-19 pandemic, the world’s attention has been focused on better understanding the relation between the human host and the SARS-CoV-2 virus, as its action has led to hundreds of thousands of deaths. Objective: In this context, we decided to study certain consequences of the abundant cytokine release over the innate and adaptive immune systems, inflammation, and hemostas...

Date: 2021   |   Origin: Oasisbr

Validation of a yellow fever vaccine model using data from primary vaccination ...

Bonin, Carla Rezende Barbosa; Fernandes, Guilherme Côrtes; Martins, Reinaldo de Menezes; Camacho, Luiz Antonio Bastos; Carvalho, Andréa Teixeira

Background: An effective yellow fever (YF) vaccine has been available since 1937. Nevertheless, questions regarding its use remain poorly understood, such as the ideal dose to confer immunity against the disease, the need for a booster dose, the optimal immunisation schedule for immunocompetent, immunosuppressed, and pediatric populations, among other issues. This work aims to demonstrate that computational too...

Date: 2021   |   Origin: Oasisbr

17DD Yellow Fever revaccination and heightened long-term immunity in population...

Campi-Azevedo, Ana Carolina; Peruhype-Magalh?es, Vanessa; Coelho-dos-Reis, Jordana Grazziela; Antonelli, Lis Ribeiro; Costa-Pereira, Christiane

Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais, Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior, Bio-Manguinhos/FIOCRUZ, PROEP/ CPqRR/FIOCRUZ, Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico?CNPq (grant nos. 444417/2014-1 and 458134/2014-7), and Programa Nacional de Imuniza??es, Secretaria de Vigil?ncia em Sa?de?Minist?rio da Sa?de, Brazil (grant no. TC 277/2013). O.A.M.-F., A...

Date: 2019   |   Origin: Oasisbr

Short-lived immunity after 17DD Yellow Fever single dose indicates that booster...

Campi-Azevedo, Ana Carolina; Reis, Laise Rodrigues; Peruhype-Magalh?es, Venessa; Reis, Jordana Grazziela Coelho dos; Antonelli, Lis Ribeiro

Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais (FAPEMIG), BioManguinhos/FIOCRUZ, PROEP/IRR/FIOCRUZ, Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico-CNPq; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Osw...

Date: 2019   |   Origin: Oasisbr

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