Background: Since the beginning of the COVID-19 pandemic, the world’s attention has been focused on better understanding the relation between the human host and the SARS-CoV-2 virus, as its action has led to hundreds of thousands of deaths. Objective: In this context, we decided to study certain consequences of the abundant cytokine release over the innate and adaptive immune systems, inflammation, and hemostas...
Background: An effective yellow fever (YF) vaccine has been available since 1937. Nevertheless, questions regarding its use remain poorly understood, such as the ideal dose to confer immunity against the disease, the need for a booster dose, the optimal immunisation schedule for immunocompetent, immunosuppressed, and pediatric populations, among other issues. This work aims to demonstrate that computational too...
Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais, Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior, Bio-Manguinhos/FIOCRUZ, PROEP/ CPqRR/FIOCRUZ, Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico?CNPq (grant nos. 444417/2014-1 and 458134/2014-7), and Programa Nacional de Imuniza??es, Secretaria de Vigil?ncia em Sa?de?Minist?rio da Sa?de, Brazil (grant no. TC 277/2013). O.A.M.-F., A...
Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais (FAPEMIG), BioManguinhos/FIOCRUZ, PROEP/IRR/FIOCRUZ, Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico-CNPq; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Osw...