53 documents found, page 1 of 6
Effect of Thymbra capitata (L.) Cav. on Inflammation, Senescence and Cell Migra...
Silva, Jorge M. Alves; Pedreiro, Sónia; Cavaleiro, Carlos; Cruz, M. Teresa; Figueirinha, Artur; Salgueiro, LígiaAromatic plants are reported to display pharmacological properties, including anti-aging. This work aims to disclose the anti-aging effect of the essential oil (EO) of Thymbra capitata (L.) Cav., an aromatic and medicinal plant widely used as a spice, as well as of the hydrodistillation residual water (HRW), a discarded by-product of EO hydrodistillation. The phytochemical characterization of EO and HRW was ass...
Vaginal Sheets with Thymbra capitata Essential Oil for the Treatment of Bacteri...
Tomás, Mariana; Sousa, Lúcia G. V.; Oliveira, Ana Sofia; Gomes, Carolina P.; Palmeira-de-Oliveira, Ana; Cavaleiro, Carlos; Salgueiro, Lígia; Cerca, NunoWe aimed to incorporate Thymbra capitata essential oil (TCEO), a potent antimicrobial natural product against bacterial vaginosis (BV)-related bacteria, in a suitable drug delivery system. We used vaginal sheets as dosage form to promote immediate relief of the typical abundant vaginal discharge with unpleasant odour. Excipients were selected to promote the healthy vaginal environment reestablishment and bioadh...
Towards the Sustainable Exploitation of Salt-Tolerant Plants: Nutritional Chara...
Lopes, Maria Celeste; Silva, Ana Sanches; Séndon, Raquel; Barbosa-Pereira, Letricia; Cavaleiro, Carlos; Ramos, FernandoIncreasing soil salinisation represents a serious threat to food security, and therefore the exploitation of high-yielding halophytes, such as Salicornia and Sarcocornia, needs to be considered not merely in arid regions but worldwide. In this study, Salicornia ramosissima and Sarcocornia perennis alpini were evaluated for nutrients, bioactive compounds, antioxidant capacity, and contaminants. Both were shown t...
Exploiting the Crithmum maritimum L. Aqueous Extracts and Essential Oil as Pote...
Pedreiro, Sónia; Figueirinha, Artur; Cavaleiro, Carlos; Cardoso, Olga; Donato, Maria Manuel; Salgueiro, Lígia; Ramos, FernandoChritmum maritimum, sea fennel, is a facultative halophyte used in salads, soups, and sauces, as well as used to prepare medicinal juices and aqueous extracts (AE) to treat several ailments. Its essential oil (EO) is used as a spice and aromatizing. In this work, the nutritional (crude protein, fiber, lipids, and ashes content) and HPLC-PDA phenolic profiles were determined. Furthermore, the antioxidant potenti...
Chemical Profile, Anti-Microbial and Anti-Inflammaging Activities of Santolina ...
Silva, Jorge Miguel Alves; Gonçalves, Maria José; Silva, Ana; Cavaleiro, Carlos; Cruz, M. Teresa; Salgueiro, LígiaFungal infections and the accompanying inflammatory responses are associated with great morbidity and mortality due to the frequent relapses triggered by an increased resistance to antifungal agents. Furthermore, this inflammatory state can be exacerbated during inflammaging and cellular senescence. Essential oils (EO) are receiving increasing interest in the field of drug discovery due to their lipophilic natu...
Cytotoxic activity of essential oil from Leaves of Myrcia splendens against A54...
Montalvão, Monalisa Martins; Felix, Franciel Batista; Propheta Dos Santos, Edmilson William; Santos, Jileno Ferreira; de Lucca Júnior, WaldecyBackground Plants of the Myrcia genus have been widely used in folk medicine to treat various diseases, including cancer. Myrcia splendens species has a diverse chemical constitution, but the biological activities of its essential oil have not been well investigated. In this study to out the chemistry characterization of essential oil (EO) from the leaves of the species M. splendens from Brazil and evaluate cyt...
Vaginal sheets with Thymbra capitata essential oil for the treatment of bacteri...
Tomás, Mariana; Sousa, Lúcia Filipa Guimarães Vieira; Oliveira, Ana Sofia; Gomes, Carolina P.; Palmeira-de-Oliveira, Ana; Cavaleiro, CarlosWe aimed to incorporate Thymbra capitata essential oil (TCEO), a potent antimicrobial natural product against bacterial vaginosis (BV)-related bacteria, in a suitable drug delivery system. We used vaginal sheets as dosage form to promote immediate relief of the typical abundant vaginal discharge with unpleasant odour. Excipients were selected to promote the healthy vaginal environment reestablishment and bioadh...
Chemical Composition and Effect against Skin Alterations of Bioactive Extracts ...
Moreira, Patrícia; Sousa, Fábio Jesus; Matos, Patrícia; Brites, Gonçalo Sousa; Gonçalves, Maria José; Cavaleiro, Carlos; Figueirinha, ArturEucalyptus globulus is planted extensively for pulp, paper and wood production. Although bioactive compounds obtained from its biomass are used as cosmetics ingredients, the skin effects were not yet fully explored. In order to fill this gap, this work aimed to study the protective effect against skin damage provided by the essential oil (EO) obtained from the hydrodistillation of Eucalyptus globulus leaves, an...
The Anti-Inflammatory Response of Lavandula luisieri and Lavandula pedunculata ...
Zuzarte, Mónica; Sousa, Cátia; Cavaleiro, Carlos; Cruz, Maria Teresa; Salgueiro, LígiaPortuguese lavenders remain undervalued in global markets due to the lack of high-quality end-products and scarcity of scientific-based studies validating their bioactive potential. Moreover, chemical variability is frequent in these species, and can compromise both safety and efficacy. In the present study, the anti-inflammatory potential of L. luisieri and L. pedunculata, two highly prevalent species in Portu...
Synergistic effects of carvacrol, α-terpinene, γ-terpinene, ρ-cymene and linalo...
Sousa, Lúcia G. V.; Castro, Joana; Cavaleiro, Carlos; Salgueiro, Lígia; Tomás, Mariana; Palmeira-Oliveira, Rita; Martinez-Oliveira, José; Cerca, NunoBacterial vaginosis (BV) is the most common vaginal infection affecting women worldwide. This infection is characterized by the loss of the dominant Lactobacillus community in the vaginal microbiota and an increase of anaerobic bacteria, that leads to the formation of a polymicrobial biofilm, mostly composed of Gardnerella spp. Treatment of BV is normally performed using broad-spectrum antibiotics, such as metr...