63 documents found, page 1 of 7
Measurement of retina/choroid complex perfusion with magnetic resonance imaging...
Ayub,Gabriel; Campos,Brunno M.; Rezende,Thiago J. R.; Cendes,Fernando; Vasconcelos,José Paulo Cabral de; Costa,Vital PaulinoABSTRACT Purpose: To measure retina/choroid complex perfusion with magnetic resonance imaging in eyes with acute primary angle-closure (APAC). Methods: Three sequences of magnetic resonance imaging, two anatomical and one perfusional using gadolinium, were acquired in patients who were diagnosed with acute primary angle-closure. Regions of interest were drawn on the perfusional sequence and overlaid to the anat...
Avaliação da resposta hemodinâmica cerebral através da monitorização com a espe...
Rein,Letícia Cristina Dalledone Siqueira; Siqueira,Daniel Emílio Dalledone; Guillaumon,Ana Terezinha; Avelar,Wagner Mauad; Cendes,FernandoResumo Contexto A espectroscopia próxima ao infravermelho (NIRS) é uma técnica não invasiva que detecta as alterações hemodinâmicas teciduais. A NIRS pode monitorar de forma contínua as informações fisiológicas vasculares intracranianas. Por ser portátil, ela pode ser utilizada à beira do leito e no centro cirúrgico. Objetivos Avaliar as possíveis alterações hemodinâmicas cerebrais durante a endarterectomia em ...
A comparative analysis of transcranial Doppler parameters acquired during carot...
Olveira,Germano da Paz; Guillaumon,Ana Terezinha; Benvindo,Sérgio Clementino; Lima,Joana Mayra Teixeira; Barreto,Sérgio Ricardo FreireAbstract Background Carotid endarterectomy (CEA) and carotid artery stenting (CAS) have both been proposed for treatment of critical atherosclerotic stenosis located at the carotid bifurcation. Monitoring of hyperintense microembolic signals (MES) by transcranial Doppler ultrasound (TCD) is considered a method of quality control, both in CEA and in CAS. Objective To analyze temporal distribution of MES througho...
Patterns of seizure control in patients with mesial temporal lobe epilepsy with...
Coan,Ana Carolina; Campos,Brunno M.; Bergo,Felipe P.G; Kubota,Bruno Y.; Yasuda,Clarissa L.; Morita,Marcia E.; Guerreiro,Carlos A.M; Cendes,FernandoObjective Patients with mesial temporal lobe epilepsy (MTLE) may present unstable pattern of seizures. We aimed to evaluate the occurrence of relapse-remitting seizures in MTLE with (MTLE-HS) and without (MTLE-NL) hippocampal sclerosis. Method We evaluated 172 patients with MTLE-HS (122) or MTLE-NL (50). Relapse-remitting pattern was defined as periods longer than two years of seizure-freedom intercalated with ...
Cortical correlates of affective syndrome in dementia due to Alzheimer’s disease
Hayata,Thaís T.; Bergo,Felipe P. G.; Rezende,Thiago J.; Damasceno,Alfredo; Damasceno,Benito P.; Cendes,Fernando; Stella,Florindo; Balthazar,Marcio L. F.Neuropsychiatric symptoms in Alzheimer’s disease (AD) are prevalent, however their relationship with patterns of cortical atrophy is not fully known. Objectives To compare cortical atrophy’s patterns between AD patients and healthy controls; to verify correlations between neuropsychiatric syndromes and cortical atrophy. Method 33 AD patients were examined by Neuropsychiatric Inventory (NPI). Patients and 29 con...
The impact of carotid revascularization on cognitive function
Oliveira,Germano da Paz; Guillaumon,Ana Terezinha; Brito,Iran Batista de; Lima,Joana Mayra Teixeira; Benvindo,Sérgio Clementino; Cendes,FernandoThe concept that carotid disease may compromise cognitive function was initially proposed by Fisher in 1951, based on an autopsy case. However, some topics involving cognitive function remain controversial, such as its correlation with carotid obstructive disease. So, the authors of this review evaluate the impact of carotid revascularization on cognitive function and the repercussions of the revascularization ...
Memory in children with symptomatic temporal lobe epilepsy
Guimarães,Catarina A.; Rzezak,Patrícia; Fuentes,Daniel; Franzon,Renata C.; Montenegro,Maria Augusta; Cendes,Fernando; Valente,Kette D.In children with temporal lobe epilepsy (TLE), memory deficit is not so well understood as it is in adults. The aim of this study was to identify and describe memory deficits in children with symptomatic TLE, and to verify the influence of epilepsy variables on memory. We evaluated 25 children with TLE diagnosed on clinical, EEG and MRI findings. Twenty-five normal children were compared with the patients. All ...
Análise comparativa do volume hipocampal e talâmico em pacientes com epilepsia ...
Leoni,Tauana B.; Coan,Ana C.; Cendes,FernandoOBJETIVO: Verificar variação no volume hipocampal e talâmico entre pacientes com epilepsia de lobo temporal mesial (ELTM) refratários ou responsivos ao tratamento medicamentoso. MÉTODOS: Foram analisados 26 pacientes com ELTM com boa resposta ao tratamento medicamentoso (grupo "benigno"), 25 refratários e 23 controles por meio do delineamento manual dos limites anatômicos do hipocampo e tálamo, em cortes sequen...
MicroRNA expression profile in epilepsy: breaking molecular barriers
Dogini,Danyella B.; Avansini,Simoni Helena; Torres,Fábio Rossi; Rogério,Fabio; Rocha,Cristiane S.; Secolin,Rodrigo; Yasuda,Clarissa L.BACKGROUND: MicroRNAs (miRNAs) are small RNA molecules (21-24 nt) that negatively regulate gene expression, either by repression of translation or by degradation of messenger RNA. These molecules are involved in many important processes including cell differentiation, neurogenesis, formation of nervous system and others. Mesial temporal lobe epilepsy and epilepsy caused by cortical dysgenesis are among the lead...
Screening symptoms of depression and suicidal ideation in people with epilepsy ...
Salgado,Priscila Camile Barioni; Nogueira,Mateus Henrique; Yasuda,Clarissa Lin; Cendes,FernandoOBJECTIVE: To measure the severity of symptoms of depression and suicidal ideation in people with epilepsy (PWE) before and after epilepsy surgery using the Beck Depression Inventory (BDI). We aimed to determine the factors associated to depression in PWE. METHODS: PWE, regardless of epilepsy type, seizure type, duration or frequency of seizures, and AEDs were investigated. The sample (n=468) was divided into t...