Introdução: Reconhecer a existência da condição pós-COVID-19; a sua prevalência e severidade é importante para definir cuidados a prestar aos doentes a longo prazo; no entanto, há poucos estudos longitudinais, em especial na doença leve a moderada. Objetivos: Identificar os sintomas persistentes ou que surgiram de novo após a infeção por COVID-19, a sua possível associação a comorbidades e conhecer o impacto da...
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Anxiety and depression are relevant comorbidities in asthma, but, in Portugal and Spain, data on this topic are scarce. We assessed, in patients with asthma, the frequency of anxiety and depression using the Hospital Anxiety and Depression Scale (HADS) and the European Quality of Life Five Dimension Questionnaire (EQ-5D); the level of agreement between these questionnaires, and the factors associated with thes...
Background: Aromatase, the cytochrome P-450 enzyme (CYP19) responsible for estrogen biosynthesis, is an important target for the treatment of estrogen-dependent breast cancer. In fact, the use of synthetic aromatase inhibitors (AI), which induce suppression of estrogen synthesis, has shown to be an effective alternative to the classical tamoxifen for the treatment of postmenopausal patients with ER-positive bre...