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People with primary progressive multiple sclerosis have a lower number of centr...

Gomes, João Manuel Canto; Da Silva-Ferreira, Sara; Silva, Carolina S.; Boleixa, Daniela; Martins da Silva, Ana; González-Suárez, Inés

The importance of circulating immune cells to primary progressive multiple sclerosis (PPMS) pathophysiology is still controversial because most immunotherapies were shown to be ineffective in treating people with PPMS (pwPPMS). Yet, although controversial, data exist describing peripheral immune system alterations in pwPPMS. This study aims to investigate which alterations might be present in pwPPMS free of dis...


Multiple Sclerosis Patient Management During the COVID-19 Pandemic: Practical R...

Cerqueira, João J.; Ladeira, Ana F.; Martins da Silva, Ana; Timóteo, Ângela; Vale, José; Sousa, Lívia; Arenga, Marta; Abreu, Pedro; Guerreiro, Rui

The spread of the COVID-19 pandemic has imposed significant challenges on healthcare provision, requiring changes in the conventional patient management, particularly in chronic diseases like multiple sclerosis (MS). To increase patient safety and reduce the risk of infection, while ensuring an appropriate and regular follow-up, tele-medicine gained prominence as a valid alternative to face-to-face appointments...


The woman who sees smaller objects: is it psychiatric or neurological?

Morgado, Pedro; Mayor, Joana Sotto; Rodrigues, Margarida; Cerqueira, João J.

Date: 2014   |   Origin: Oasisbr

Stress affects theta activity in limbic networks and impairs novelty-induced ex...

Jacinto, Luís; Reis, Joana; Dias, Nuno S.; Cerqueira, João J.; Correia, José Higino; Sousa, Nuno

Exposure to a novel environment triggers the response of several brain areas that regulate emotional behaviors. Here, we studied theta oscillations within the hippocampus (HPC)-amygdala (AMY)-medial prefrontal cortex (mPFC) network in exploration of a novel environment and subsequent familiarization through repeated exposures to that same environment; in addition, we assessed how concomitant stress exposure cou...

Date: 2013   |   Origin: CiencIPCA

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