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Neuregulin-1 improves right ventricular function and attenuates experimental pu...

Mendes-Ferreira, P.; Maia-Rocha, C.; Adão, R.; Mendes, M.J.; Santos-Ribeiro, D.; Silvana Alves, B.; Cerqueira, R.J.; Castro-Chaves, P.; Lourenço, A.P.

Aims Pulmonary arterial hypertension (PAH) is a serious disease that affects both the pulmonary vasculature and the right ventricle (RV). Current treatment options are insufficient. The cardiac neuregulin (NRG)-1/ErbB system is deregulatedduring heart failure, and treatment with recombinant human NRG-1 (rhNRG-1) has been shown to be beneficial inanimal models and in patients with left ventricular (LV) dysfuncti...


A neuregulina-1 atenua a disfunção endotelial na hipertensão arterial pulmonar

Mendes-Ferreira, P.; Adão, R.; Cerqueira, R.J.; Maia-Rocha, C.; Mendes, M.J.; Castro-Chaves, P.; De Keulenaer, G.W.; Leite-Moreira, A.F.

[abstract]


Neuregulin attenuates pulmonary endothelial dysfunction in pulmonary hypertension

Mendes-Ferreira, P.; Adão, R.; Maia-Rocha, C.; Cerqueira, R.J.; Mendes, M.J.; Castro-Chaves, P.; De Keulenaer, G.W.; Leite-Moreira, A.F.

[abstract]


NRG-1 improves monocrotaline-induced right ventricular and pulmonary endothelia...

Mendes-Ferreira, P.; Maia-Rocha, C.; Adao, R.; Cerqueira, R.J.; Mendes, M.J.; Lourenco, A.P.; Pinho, S.; De Keulenaer, G.W.; Leite-Moreira, A.F.

[abstract]


Neuregulin attenuates pulmonary endothelial dysfunction in an experimental mode...

Adão, R.; Maia-Rocha, C.; Mendes-Ferreira, P.; Mendes, M.J.; Cerqueira, R.J.; Castro-Chaves , P.; De Keulenaer, G.W.; Leite-Moreira, A.F.

[abstract]


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