Aims Pulmonary arterial hypertension (PAH) is a serious disease that affects both the pulmonary vasculature and the right ventricle (RV). Current treatment options are insufficient. The cardiac neuregulin (NRG)-1/ErbB system is deregulatedduring heart failure, and treatment with recombinant human NRG-1 (rhNRG-1) has been shown to be beneficial inanimal models and in patients with left ventricular (LV) dysfuncti...
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