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The influence of leprosy-related clinical and epidemiological variables in the ...

Cerqueira, Selma Regina Penha Silva; Deps, Patrícia Duarte; Cunha, Débora Vilela; Bezerra, Natanael Victor Furtunato; Barroso, Daniel Holanda

Background Protective effects of Bacillus Calmette–Gue´rin (BCG) vaccination and clofazimine and dapsone treatment against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported. Patients at risk for leprosy represent an interesting model for assessing the effects of these therapies on the occurrence and severity of coronavirus disease 2019 (COVID-19). We assessed the influenc...

Date: 2022   |   Origin: Oasisbr

O risco de infecção por SARS-CoV-2 nos pacientes com hanseníase e seus contacta...

Cerqueira, Selma Regina Penha Silva

Tese (doutorado) — Universidade de Brasília, Faculdade de Ciências Médicas, Programa de Pós-Graduação em Ciências Médicas, 2021.; Efeitos protetores da vacinação com Bacillus Calmette-Guérin (BCG) e tratamento com clofazimina e dapsona contra infecção pelo novo coronavírus (SARS-CoV-2) foram relatados. Pacientes em risco de hanseníase representam um modelo interessante para avaliar os efeitos de tais terapias s...

Date: 2022   |   Origin: Oasisbr

Enhanced il-6 and il-12b gene expression after SARS-CoV-2 infection in leprosy ...

Morais Júnior, Gilberto Santos; Kurizky, Patricia Shu; Cerqueira, Selma Regina Penha Silva; Barroso, Daniel Holanda; Schulte, Heidi Luise

Experts have called attention to the possible negative impact of the coronavirus disease 2019 (COVID19)–related cytokine storm syndrome on the progression of leprosy-related disabilities. We assessed the frequency of reactional states in patients co-infected with Mycobacterium leprae and severe acute respiratory syndrome (SARS) coronavirus (CoV) 2 (SARS-CoV-2). We consecutively included patients during the firs...

Date: 2021   |   Origin: Oasisbr

Enhanced il-6 and il-12b gene expression after SARS-CoV-2 infection in leprosy ...

Morais Júnior, Gilberto Santos; Kurizky, Patricia Shu; Cerqueira, Selma Regina Penha Silva; Barroso, Daniel Holanda; Schulte, Heidi Luise

Experts have called attention to the possible negative impact of the coronavirus disease 2019 (COVID-19)–related cytokine storm syndrome on the progression of leprosy-related disabilities. We assessed the frequency of reactional states in patients co-infected with Mycobacterium leprae and severe acute respiratory syndrome (SARS) coronavirus (CoV) 2 (SARS-CoV-2). We consecutively included patients during the fir...

Date: 2021   |   Origin: Oasisbr

SARS-CoV-2/DENV co-infection : a series of cases from the Federal District, Mid...

Schulte, Heidi Luise; Sousa, José Diego Brito; Lacerda, Marcus Vinícius Guimarães de; Naves, Luciana Ansaneli; Gois, Eliana Teles de

Background: Since the novel coronavirus disease outbreak, over 179.7 million people have been infected by SARS-CoV-2 worldwide, including the population living in dengue-endemic regions, particularly Latin America and Southeast Asia, raising concern about the impact of possible co-infections. Methods: Thirteen SARS-CoV-2/DENV co-infection cases reported in Midwestern Brazil between April and September of 2020 a...

Date: 2021   |   Origin: Oasisbr

Interferência da polimedicação no tratamento da hanseníase : um estudo caso-con...

Cerqueira, Selma Regina Penha Silva

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Medicina, Programa de Pós-Graduação em Ciências Médicas, 2019.; Introdução: A hanseníase é caracterizada por um quadro infectocontagioso, causado pelo Mycobacterium leprae, evoluindo de forma lenta e gradativa, com a manifestação de sinais e sintomas dermatoneurológicos. Nesse sentido, aplica-se o tratamento baseado na poliquimioterapia (PQT). Essa e...

Date: 2020   |   Origin: Oasisbr

The challenge of concomitant infections in the coronavirus disease 2019 pandemi...

Kurizky, Patricia Shu; Cerqueira, Selma Regina Penha Silva; Cunha, Débora Vilela; Albuquerque, Cleandro Pires de; Aires, Rodrigo Barbosa

Coronavirus disease 2019 (COVID-19) was first officially described in Brazil on February 26th, 2020. The accumulation of reports of concomitant infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and pathogens that cause diseases endemic to tropical countries, such as dengue and chikungunya fever, has started to draw attention. Chagas disease and leprosy remain public health problems in...

Date: 2020   |   Origin: Oasisbr

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