3 documents found, page 1 of 1
Association between BRAF (V600E) mutation and clinicopathological features of p...
Pessôa-Pereira,Danielle; Medeiros,Mateus Fernandes da Silva; Lima,Virna Mendonça Sampaio; Silva Jr.,Joaquim Custódio daABSTRACT Objectives: We aimed to investigate the prevalence of the BRAF (V600E) mutation in consecutive cases of papillary thyroid carcinoma (PTC) in patients diagnosed and treated at the Hospital Sao Rafael (Salvador, BA, Brazil) and evaluate its association with clinical and pathological characteristics of PTC. Subjects and methods: We retrospectively enrolled in the study a total of 43 consecutive PTC patien...
Mutation screening in the genes PAX-8, NKX2-5, TSH-R, HES-1 in cohort of 63 Bra...
Cerqueira,Taíse Lima de Oliveira; Ramos,Yanne Rocha; Strappa,Giorgia Bruna; Jesus,Mariana Souza de; Santos,Jailciele Gonzaga; Sousa,CamilaABSTRACT Objective: To evaluate the candidate genes PAX-8, NKX2-5, TSH-R and HES-1 in 63 confirmed cases of thyroid dysgenesis. Subjects and methods: Characterization of patients with congenital hypothyroidism into specific subtypes of thyroid dysgenesis with hormone levels (TT4 and TSH), thyroid ultrasound and scintigraphy. DNA was extracted from peripheral blood leukocytes and the genetic analysis was realize...
Iodine nutritional status in Brazil: a meta-analysis of all studies performed i...
Campos,Renata de Oliveira; Barreto,Iasmin dos Santos; Maia,Lorena Rejane de Jesus; Rebouças,Sara Cristina Lima; Cerqueira,Taíse Lima de OliveiraObjectives Iodine deficiency disorder (IDD) is the result of an inadequate dietary intake of iodine, which physiological consequences are endemic goiter and thyroid dysfunction. The objective of this study was to a analyze studies that assessed the status of Brazil’s population iodine nutrition and IDD prevalence. Materials and methods Systematic review using PRISMA statement. Electronic database: PubMed, Medli...