Introduction: Avacopan, a selective C5a receptor inhibitor, has emerged as a potential corticosteroid-sparing treatment in ANCA-associated vasculitis (AAV). This study aims to evaluate its real-world efficacy and safety in Portuguese patients with active AAV. Methods: We conducted a multicenter retrospective analysis of 15 adult patients with newly diagnosed or relapsing AAV treated with avacopan across nine ac...
Rare systemic rheumatic diseases (RISD) with renal involvement, such as anti‑neutrophil cytoplasmic antibody (ANCA)‑associated vasculitis and systemic lupus erythematosus, require complex, coordinated care. These conditions often involve renal complications requiring specialized and timely intervention. Traditional care models, typically fragmented across specialties, are insufficient to meet the nuanced needs ...