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Asymmetric dimethylarginine (ADMA) and endothelial dysfunction: implications fo...

Landim, Maurício Batista Paes; Casella Filho, Antônio; Chagas, Antônio Carlos Palandri

Atherosclerotic coronary heart disease is the leading cause of morbidity and mortality in industrialized countries, and endothelial dysfunction is considered a precursor phenomenon. The nitric oxide produced by the endothelium under the action of endothelial nitric oxide synthase has important antiatherogenic functions. Its reduced bioavailabilty is the beginning of the atherosclerotic process. The addition of ...

Date: 2009   |   Origin: Oasisbr

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