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Eicosapentaenoic acid and docosahexaenoic acid exert anti-inflammatory and anti...

Nobre, Maria Elizabeth Pereira; Correia, Alyne Oliveira; Borges, Marília de Brito; Sampaio, Thayga Maria Araújo; Chakraborty, Solon Arcoverde

In the present study, we evaluated omega-3 polyunsaturated fatty acid (PUFA) (consisting of 20:5n-3 and 22:6n-3) properties on inflammation and nociception. Among the in vivo tests, writhing, formalin, and hot plate tests were conducted in mice, and carrageenan-induced paw edema, peritonitis, and Hargreaves tests were performed in rats. Following the carrageenaninduced edema, immunohistochemistry for tumor necr...

Date: 2014   |   Origin: Oasisbr
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