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The novel ECF56 SigG1-RsfG system modulates morphological differentiation and m...

Oliveira, R; Bush, MJ; Pires, SDS; Chandra, G; Casas-Pastor, D; Fritz, G; Mendes, MV

Extracytoplasmic function (ECF) sigma factors are key transcriptional regulators that prokaryotes have evolved to respond to environmental challenges. Streptomyces tsukubaensis harbours 42 ECFs to reprogram stress-responsive gene expression. Among them, SigG1 features a minimal conserved ECF s2–s4 architecture and an additional C-terminal extension that encodes a SnoaL_2 domain, which is characteristic for ECF ...

Date: 2020   |   Origin: Repositório Aberto da Universidade do Porto
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