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Optimization of the molecular diagnosis of the acute hepatitis E virus infection

Lopez-Lopez, P; Frias, M; Perez-Jimenez, AB; Freyre-Carrillo, C; Pineda, JA; Aguilera, A; Fuentes, A; Alados, JC; Reina, G; Ramirez-Arellano, E

To evaluate the diagnostic value of the combination of two broad-range PCR assays targeting two different and conserved regions of the viral genome for the diagnosis of acute Hepatitis E virus (HEV) infection. Patients with acute hepatitis were prospectively recruited. In all, HEV-IgM antibodies were tested together with evaluation of HEV viraemia by two PCR assays (ORF3 and ORF1). The number of individuals exh...


Survey of Zoonotic Diarrheagenic Protist and Hepatitis E Virus in Wild Boar (Su...

Santos-Silva, S; Moraes, DFDD; Lopez-Lopez, P; Palmeira, JD; Torres, RT; Nascimento, MS; Dashti, A; Carmena, D; Rivero-Juarez, A; Mesquita, JR

Simple Summary Enteropathogenic viruses, such as hepatitis E virus, and diarrhoeagenic protists have been frequently reported in swine and can infect a wide range of mammals, including humans. Data on their fecal shedding and circulation pathways are still lacking or incomplete. Hence, the aim of the present study was to characterize the presence of microeukaryotes and HEV in the wild boar of Portugal. Of the 1...


A Systematic Review of Hepatitis E Virus Detection in Camels

Santos-Silva, S; Hemnani, M; Lopez-Lopez, P; Gonçalves, HMR; Rivero-Juarez, A; van der Poel, WHM; Nascimento, MSJ; Mesquita, JR

Simple Summary: Acute hepatitis, which is a rising public health issue globally, is mostly caused by the hepatitis E virus (HEV). There is a potential risk of camel-borne zoonotic HEV infection in the desert regions of the Middle East and Africa, where camels frequently interact with human populations and camel-derived food products constitute a component of the food chain. To better understand the current stat...


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