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Assessment of Novel C-4 Methylated Tetraketide by HPLC-SPE-TT in Saccharicola s...

Borges,Maiara S.; Biasetto,Carolina R.; Chapla,Vanessa M.; Ebrahimi,Samad N.; Costa,Mayra F.; Bolzani,Vanderlan S.; Araujo,Angela R.

A new compound named methyl (6S,7S,2E,4E)-6,7-dihydroxy-4,6-dimethyl octanoate was isolated from Saccharicola sp. using high performance liquid chromatography-solid phase extraction-transfer tube (HPLC-SPE-TT), together with four known compounds, fusaric acid, trans-4-hydroxymellein, thymidine and adenosine. Saccharicola sp. was isolated from the stems of Eugenia jambolana Lam. (Myrtaceae) as endophytic fungus....

Date: 2019   |   Origin: Oasisbr

Griseofulvin, Diketopiperazines and Cytochalasins from Endophytic Fungi Colleto...

Chapla,Vanessa M.; Zeraik,Maria L.; Cafeu,Mariana C.; Silva,Geraldo H.; Cavalheiro,Alberto J.; Bolzani,Vanderlan S.; Young,Maria C. M.

One new natural product, 1-phenylethyl-O-a-L-rhamnopyranoside, together with eight known diketopiperazines and two benzene derivatives were isolated from the endophytic fungus Colletotrichum crassipes, whereas six known compounds including two griseofulvins, three cytochalasins and one dihydroisocoumarin were produced from the endophyte Xylaria sp., both endophytic fungi are associated with leaves of Casearia s...

Date: 2018   |   Origin: Oasisbr

Antimicrobial Screening of Endophytic Fungi Isolated from the Aerial Parts of P...

Hilário,Felipe; Chapla,Vanessa M.; Araujo,Angela R.; Sano,Paulo T.; Bauab,Taís M.; Santos,Lourdes C. dos

The screening for antimicrobial activity of twenty five endophytic fungi isolated from the aerial parts of Paepalanthus chiquitensis (Eriocaulaceae) was assayed against the bacteria Gram-positive Staphylococcus aureus, Gram-negative Escherichia coli and Salmonella setubal, and the yeast fluconazole-resistant Candida albicans. The ethyl acetate extract produced by Fusarium fujikuroi was the most bioactive and th...

Date: 2017   |   Origin: Oasisbr

ONE STRAIN-MANY COMPOUNDS (OSMAC) METHOD FOR PRODUCTION OF PHENOLIC COMPOUNDS U...

Gubiani,Juliana R.; Habeck,Thomas R.; Chapla,Vanessa M.; Silva,Geraldo H.; Bolzani,Vanderlan S.; Araujo,Angela R.

Seven phenolic derivatives including p-hydroxyphenyllactic acid (1), p-hydroxybenzoic acid (2), p-hydroxybenzaldehyde (3), phenyllactic acid (4), n-butyl-3,4-dihydroxybenzoate (5), n-hexyl-3,4-dihydroxybenzoate (6) and n-octyl-3,4-dihydroxybenzoate (7) were produced using Camarops sp. via the one strain-many compounds (OSMAC) approach. Their structures were determined using 2D NMR and ESI-MS spectra and were co...

Date: 2016   |   Origin: Oasisbr

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