19 documents found, page 1 of 2
Zebrafish as a model to study inflammation: A tool for drug discovery
Belo, Marco A.A. [UNESP]; Oliveira, Melque F.; Oliveira, Susana L. [UNESP]; Aracati, Mayumi F. [UNESP]; Rodrigues, Letícia F. [UNESP]Made available in DSpace on 2022-04-28T19:45:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); This study aims to demonstrate the applicability and importance of zebrafish (Danio rerio) model to study acute and chronic inflammatory responses induced by different sti...
Shedding light on the toxicity of SARS-CoV-2-derived peptide in non-target COVI...
da Luz, Thiarlen Marinho; Araújo, Amanda Pereira da Costa; Rezende, Fernanda Neves Estrêla; Silva, Abner Marcelino; Charlie-Silva, IvesMade available in DSpace on 2022-04-28T19:52:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-05-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Despite advances in research on the vaccine and therapeutic strategies of COVID-19, little attention has been paid to the possible (eco)toxicological impacts of the dispersion of SARS-CoV-2 particles in natural environments. Thus, in ...
Environmental impacts of COVID-19 treatment: Toxicological evaluation of azithr...
Mendonça-Gomes, Juliana Moreira; da Costa Araújo, Amanda Pereira; da Luz, Thiarlen Marinho; Charlie-Silva, Ives; Braz, Helyson Lucas BezerraMade available in DSpace on 2022-04-29T08:45:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-10; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); One of the most impact issues in recent years refers to the COVID-19 pandemic, the consequences of which thousands of deaths recorded worldwide, are still inferior understood. Its impacts on the environment and aquatic biota constitut...
Toxicological insights of Spike fragments SARS-CoV-2 by exposure environment: A...
Charlie-Silva, Ives; Araújo, Amanda P.C.; Guimarães, Abraão T.B.; Veras, Flávio P.; Braz, Helyson L.B.; de Pontes, Letícia G.; Jorge, Roberta J.B.Made available in DSpace on 2022-04-29T08:45:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-05; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The Spike protein (S protein) is a critical component in the infection of the new coronavirus (SARS-CoV-2). The objective of this work was to evaluate whether peptides fro...
Shedding light on toxicity of SARS-CoV-2 peptides in aquatic biota: A study inv...
Mendonça-Gomes, Juliana Moreira; Charlie-Silva, Ives; Guimarães, Abraão Tiago Batista; Estrela, Fernanda Neves; Calmon, Marilia Freitas [UNESP]Made available in DSpace on 2022-04-29T08:45:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-15; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Instituto Federal Goiás; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Knowledge about how the COVID-19 pandemic can affect aquatic wildlife is still extremely limited, and no effect of SARS-CoV-2 or its structural co...
Toxicity of spike fragments SARS-CoV-2 S protein for zebrafish: A tool to study...
Ventura Fernandes, Bianca H.; Feitosa, Natália Martins; Barbosa, Ana Paula; Bomfim, Camila Gasque; Garnique, Anali M.B.; Rosa, Ivana F. [UNESP]Made available in DSpace on 2022-04-29T08:46:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-20; Ministério da Ciência, Tecnologia e Inovação; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Despite the significant increase in the generation of SARS-CoV-2 contaminated domestic and hospital wastewater, little is kno...
Toxicological impact of SARS-CoV-2 on the health of the neotropical fish, Poeci...
Malafaia, Guilherme; Ahmed, Mohamed Ahmed Ibrahim; Souza, Sindoval Silva de; Rezende, Fernanda Neves Estrela; Freitas, Ítalo NascimentoMade available in DSpace on 2022-04-29T08:46:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-04-01; There have been significant impacts of the current COVID-19 pandemic on society including high health and economic costs. However, little is known about the potential ecological risks of this virus despite its presence in freshwater systems. In this study, we aimed to evaluate the exposure of Poecilia r...
Recent advances in SARS-CoV-2 Spike protein and RBD mutations comparison betwee...
Sanches, Paulo R.S. [UNESP]; Charlie-Silva, Ives; Braz, Helyson L.B.; Bittar, Cíntia [UNESP]; Freitas Calmon, Marilia [UNESP]; Rahal, Paula [UNESP]Made available in DSpace on 2022-05-01T09:30:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); New variants of SARS-CoV-2 Alpha (B.1.1.7); Beta (B.1.351) Gamma (P.1) and Delta (B.1.617.2) quickly spread in the UK, South Africa, Brazil and India, respectively. To address whether mutations in SARS-CoV-2 RBD spike protein could affect vi...
Astaxanthin improves the shelf-life of tilapia fillets stored under refrigeration
Aracati, Mayumi Fernanda [UNESP]; Rodrigues, Leticia Franchin [UNESP]; de Oliveira, Susana Luporini [UNESP]; Rodrigues, Romário Alves [UNESP]Made available in DSpace on 2022-05-01T13:41:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; BACKGROUND: Astaxanthin, classified as a xanthophyll, has antioxidant properties about 500 times greater than α-tocopherols and ten times greater than β-carotenes. Based on the antioxidant activity of this carotenoid, this study aimed to evaluate the shelf-life of tilapia fillets (Oreochromis niloticus)...
Cyclophosphamide modulated the foreign body inflammatory reaction in tilapia (O...
Charlie-Silva, Ives; Conde, Gabriel [UNESP]; Mendonça Gomes, Juliana Moreira; Johnny da Rosa Prado, Ed [UNESP]; Fernandes, Dayanne Carla [UNESP]Made available in DSpace on 2021-06-25T10:13:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); In order to understand events and mechanisms present in the pathophysiology of tilapia's chronic inflammation and based on the immunomodulatory activity attributed to cycl...