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Immunoblot evaluation of rubella humoral immunity in Portuguese women with nega...

Chasqueira, Maria-Jesus; Costa, Sara; Paixão, Margarida; Albuquerque, Margarida; Rego, Maria José Sousa; Paixão, Paulo

Despite its low incidence in Europe, rubella's immune status is still routinely assessed using commercial immunoassays. However, some discrepancies have been observed between these tests and the Immunoblot. The main objective of this study is to evaluate, by a commercial immunoblot, the immune status of a female population that had previously presented negative, low-positive, or equivocal rubella IgG with a com...


SARS-CoV-2 Infection in Children

Martins, Catarina; Ângelo-Dias, Miguel; Chasqueira, Maria-Jesus; Brito, Maria João; Silva, Tiago Milheiro; Matos, Maria Vitória; Lopes, Maria Teresa

Children with COVID-19 typically experience milder symptoms and lower hospitalization rates, though severe cases do occur. Understanding age-related immune responses is crucial for future preparedness. We characterized immune response dynamics to SARS-CoV-2 in 145 samples from 119 pediatric patients (<18 years) with confirmed infection, assessed at four distinct time points: <14 days, 14 days-3 months, 3-6 mont...


Genetic and Epidemiological Insights Into Respiratory Syncytial Virus Infections

Lança, Miguel; Gaio, Vânia; Rodrigues, Ana Paula; Henriques, Camila; Gomes, Licínia; Dias, Daniela; Chasqueira, Maria-Jesus; Guiomar, Raquel

Funding Information: Funding: The authors received no specific funding for this work. We gratefully acknowledge all data contributors, authors and their originating laboratories and the contribution of all physicians that collaborated in the VigiRSV network (VigiRSV network: Teresa Gouveia, Regina Viseu, Maria Zarcos, Ricardo Castro, Jorge Rodrigues, Virg\u00EDnia Martinez, Eurico Jorge Gaspar, Carlos Caldas, E...


Antimicrobial Resistance Genes in Legionella from Artificial Water Systems

Pereira, Bernardo Beirão; Marrafa, Mário; Cruz, Carolina; Rodrigues, Lúcia; Nunes, Filipa; Monteiro, Silvia; Santos, Ricardo; Carneiro, Rui Neves

Background: Legionella species are the causative agent of Legionnaires’ disease and, as ubiquitous waterborne bacteria, are prone to antimicrobial resistance gene (ARG) acquisition and dissemination due to the antimicrobial contamination of natural environments. Given the potential health risks associated with ARGs, it is crucial to assess their presence in the Legionella population. Methods: The ARGs lpeAB and...


Corrigendum

Cruz, Carolina; Rodrigues, Lúcia; Fernandes, Filipa; Santos, Ricardo; Paixão, Paulo; Chasqueira, Maria-Jesus

Publisher Copyright: Copyright © 2023 Cruz, Rodrigues, Fernandes, Santos, Paixão and Chasqueira.; [This corrects the article DOI: 10.3389/fcimb.2023.1141115.].


Pooling Saliva Sample as an Effective Strategy for the Systematic CMV Screening...

Chasqueira, Maria-Jesus; Fernandez, Catarina; Marques, Augusta; Rodrigues, Lucia; Marçal, Mónica; Tuna, Madalena; Braz, Monica; S Neto, Ana

BACKGROUND: Cytomegalovirus is the most common cause of congenital infections worldwide. Screening all newborns in the first 2 weeks of life is the only way to detect all cases of congenital infection, allowing the monitoring of children with asymptomatic infection at birth and early intervention. AIM: In this multicenter study, we aimed to evaluate the feasibility of using a saliva pool strategy for mass scree...


Antibiotic susceptibility pattern of Portuguese environmental Legionella isolates

Cruz, Carolina; Rodrigues, Lúcia; Fernandes, Filipa; Santos, Ricardo; Paixão, Paulo; Chasqueira, Maria-Jesus

Publisher Copyright: Copyright © 2023 Cruz, Rodrigues, Fernandes, Santos, Paixão and Chasqueira.; Introduction: Legionnaires’ Disease is a pneumonia caused by Legionella spp., currently treated empirically with fluoroquinolones and macrolides. In this study, we aim to describe the antibiotic susceptibility pattern of environmental Legionella recovered in the south of Portugal. Methods: Minimal inhibitory concen...


Lower prevalence of congenital cytomegalovirus infection in Portugal: possible ...

Fernandez, Catarina; Chasqueira, Maria-Jesus; Marques, Augusta; Rodrigues, Lúcia; Marçal, Mónica; Tuna, Madalena; Braz, Mónica Cró; Neto, Ana Serrão


Lower prevalence of congenital cytomegalovirus infection in Portugal

Fernandez, Catarina; Chasqueira, Maria-Jesus; Marques, Augusta; Rodrigues, Lúcia; Marçal, Mónica; Tuna, Madalena; Braz, Mónica Cró; Neto, Ana Serrão

59301]. Publisher Copyright: © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.; Cytomegalovirus (CMV) is the most frequent cause of congenital infection all over the world. Its prevalence ranges from 0.2 to 2.2%. Transmission from children to their pregnant mothers is a well-known risk factor, particularly if they attend a childcare centre. This study aims ...


Respiratory viruses in mechanically ventilated patients

Nazareth, Raquel; Chasqueira, Maria-Jesus; Rodrigues, Maria Lúcia; Paulino, Carolina; Conceição, Catarina; Lêdo, Lia; Segura, Úrsula; Santos, Madalena

BACKGROUND: Respiratory virome is an integral part of the human microbiome and its characterization may contribute to a better understanding of the changes that arise in the disease and, consequently, influence the approach and treatment of patients with acute lower respiratory infections. The aim of this study was to evaluate the presence of respiratory viruses in the lower airways of individuals undergoing in...


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