2 documents found, page 1 of 1
Reading of the Mitsuda test: comparison between diameter and total area by mean...
Alecrim, Edilamar Silva de; Chaves, Ana Thereza; Pôrto, Luiz Alberto Bomjardim; Grossi, Maria Aparecida de Faria; Lyon, SandraThe Mitsuda test is a skin test based on the individual’s immune response through late and highly specific hypersensitivity reaction to the Mycobacterium leprae bacillus. A negative reaction identifies individuals who present a higher risk of becoming ill if exposed to M. leprae and, if they become ill, to develop the virchowian form of disease. The Mitsuda test reading is performed by means of a millimeter rul...
Immunogenomic screening approach to identify new antigens for the serological d...
Elisei, Rutyanne Maria Tonelli; Matos, Christiane Santos; Carvalho, Ana Maria Ravena Severino; Chaves, Ana Thereza; Medeiros, Fernanda Alvarenga CardosoSerological tests are preferentially used for the diagnosis of Chagas’ disease (CD) during the chronic phase because of the low parasitemia and high anti-Trypanosoma cruzi antibody titers. However, the current methods showed several disadvantages, as contradictory or inconclusive results, mainly related to the characteristics of the antigens used, in general, crude or whole parasites, but also due to antigen pr...