19 documents found, page 1 of 2

Ocimum gratissimum essential oil improved the health, innate immunity and resis...

Made available in DSpace on 2022-04-29T08:35:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The essential oil of alfavaca (Ocimum gratissimum) contains important compounds, such as 1.8-cineol and eugenol. This study evaluated the effects of diets containing alfavaca essential oil on the zootechnical performance, plasma gluco...

Eficácia in vitro de óleos essenciais de espécies de Piperaceae no controle do ...

This study investigated the in vitro efficacy of essential oils (OEs) of four species of plants of the family Piperaceae, these being; Piper hispidinervum, Piper hispidum, Piper marginatum and Piper callosum, in the control of Neoechinorhynchus buttnerae acanthocephalus that affect tambaqui. The tested concentrations of OE were: 0.19; 0.39; 0.78; 1.56; 3.125; 6.25; 12.5; 25 and 50 mg.mL-1, in triplicate, into p...

Adulticidal activity of dillapiol and semi-synthetic derivatives of dillapiol a...

Stability and antioxidant activity of semi-synthetic derivatives of 4-nerolidyl...

4-nerolidylcatechol (4-NC) is an unstable natural product that exhibits important antioxidant, anti-inflammatory and other properties. It is readily obtainable on a multi-gram scale through straightforward solvent extraction of the roots of cultivated Piper peltatum or P. umbellatum, followed by column chromatography on the resulting extract. Semi-synthetic derivatives of 4-NC with one or two substituent groups...

Biomass production in cultivated Pothomorphe peltata Miq. (Piperaceae) as a fun...

In vivo antimalarial activity and mechanisms of action of 4-nerolidylcatechol d...

4-Nerolidylcatechol (1) is an abundant antiplasmodial metabolite that is isolated from Piper peltatum roots. O-Acylation or O-alkylation of compound 1 provides derivatives exhibiting improved stability and significant in vitro antiplasmodial activity. The aim of this work was to study the in vitro inhibition of hemozoin formation, inhibition of isoprenoid biosynthesis in Plasmodium falciparum cultures, and in v...

In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon

Background: The anti-malarials quinine and artemisinin were isolated from traditionally used plants (Cinchona spp. and Artemisia annua, respectively). The synthetic quinoline anti-malarials (e.g. chloroquine) and semi-synthetic artemisinin derivatives (e.g. artesunate) were developed based on these natural products. Malaria is endemic to the Amazon region where Plasmodium falciparum and Plasmodium vivax drug-re...

In vitro susceptibility of Plasmodium falciparum Welch field isolates to infusi...

Artemisinin is the active antimalarial compound obtained from the leaves of Artemisia annua L. Artemisinin, and its semi-synthetic derivatives, are the main drugs used to treat multi-drug-resistant Plasmodium falciparum (one of the human malaria parasite species). The in vitro susceptibility of P. falciparum K1 and 3d7 strains and field isolates from the state of Amazonas, Brazil, to A. annua infusions (5 g dry...

Registro da 1ª Jornada Amazonense de Plantas Medicinais

Effects of culture filtrates of endophytic fungi obtained from Piper aduncum L....

Substances that inhibit the growth of Mycobacterium tuberculosis could potentially be used as antibiotics. These substances could also be added to test culture media to improve the speed of tuberculosis diagnosis. The aim of this work was to investigate the influence of culture filtrates of endophytic fungi isolated from P. aduncum L. on the growth of M. tuberculosis. To achieve this objective, the following me...